LP6463-6     Probe with signal amplification

  Part: Probe.amp.sig
  Description: Signal amplification method that includes Hybridization Protection Assay (HPA) which applies to RNA, and Branched chain DNA (bDNA) which applies to DNA and RNA.
  Part: Probe.amp.sig
  Description: Probe with signal amplification is a lab method that uses a hybridization probe, which is a typically a short nucleic acid segment that binds to a complementary nucleic acid sequence that is specific to the target of interest, followed by a signal enhancement step, in which the signal that is generated when the probe binds to the target sequence is multiplied so that it is “brighter” and easier to detect. Signal amplification can be done using different techniques, including the branched-chain DNA (bDNA) method. In theory, signal amplification is more sensitive than a probe by itself because it generates a brighter signal per each copy of the target sequence that is present. In LOINC, the probe.amp.sig method is assigned to codes for assays that do not include a nucleic acid amplification step.

  Part: Probe.amp.sig
  Construct for LOINC short name: Probe+sig amp
  Type: METHOD
  Status: ACTIVE
  Created On: 5/3/2000

  Chinese (CHINA)  (From: Lin Zhang, A LOINC volunteer from China)   SYNONYMS
  探针法.基因扩增.信号     借助信号扩增的探针方法;借助信号扩增的探针法;探针法.扩增.信号;支链 DNA;支链 DNA(Branched Chain DNA,bDNA);杂交保护分析;杂交保护分析(Hybidization Protection Assay,HPA);杂交保护测定;杂种捕获;杂种捕获(Hybrid Capture);杂种捕获核酸杂交(Hybrid Capture nucleic acid hybridization)
  Dutch (NETHERLANDS)  (From: NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)    
  French (BELGIUM)  (From: Jean M. Prevost, MD, Biopathology)    
  Sonde avec amplification du signal      
  French (CANADA)  (From: Canada Health Infoway Inc.)    
  Sonde avec amplification du signal      
  Greek (GREECE)  (From: Efstratia Kontaxi, MD, MSc, and Evripidis Stefanidis, MD, with technical support from Panagiotis Kontaxis, Diploma of Electrical and Computer Engineering.)    
  Ανιχνευτής με ενίσχυση σήματος      
  Italian (ITALY)  (From: Consiglio Nazionale delle Ricerche)   SYNONYMS
  Sonda.amp.sig     Sonda con amplificazione del segnale
  Russian (RUSSIAN FEDERATION)  (From: Yaroslavl State Medical Academy)   SYNONYMS
  Проба.усил.сигн     Проба с сигнала усилением
  Spanish (SPAIN)  (From: the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)   SYNONYMS
  Sonda con amplificación de señal     bDNA
  Turkish (TURKEY)  (From: LOINC Turkish Translation Group and the Turkish Ministry of Health)    

  Detail Page Created On: 6/20/2019 3:42:31 PM
  Display name: Probe with signal amplification
  Preferred Abbreviation: Probe+sig amp