LP16428-2     Hemoglobin F

  Part: Hemoglobin F
  Description: Hemoglobin F is used to screen for fetal-to-maternal hemorrrhage. The presence of fetal red cells in the maternal circulation may be identified by use of the acid elution principle first described by Kleihauer, Brown, and Betke, or by several modifications. Very small volumes of red cells commonly escape from the fetal intravascular compartment across the placental barrier into the maternal intervillous space.
  Part: Hemoglobin F
  Description: Fetal hemoglobin, or foetal haemoglobin, (also hemoglobin F or HbF) is the main oxygen transport protein in the fetus during the last seven months of development in the uterus and in the newborn until roughly 6 months old. Functionally, fetal hemoglobin differs most from adult hemoglobin in that it is able to bind oxygen with greater affinity than the adult form, giving the developing fetus better access to oxygen from the mother's bloodstream.

In newborns, fetal hemoglobin is nearly completely replaced by adult hemoglobin by approximately 6 months postnatally. In adults, fetal hemoglobin production can be reactivated pharmacologically, which is useful in the treatment of diseases such as sickle-cell disease.
  Copyright: Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.

  Construct for LOINC short name: Hgb F
  Status: ACTIVE
  Created On: 5/4/2000

  Part: Hemoglobin F
  Description: Fibach E, Flow cytometric analysis of fetal hemoglobin in RBC and their precursors.

  Chinese (CHINA)  (From: Lin Zhang, A LOINC volunteer from China)   SYNONYMS
  血红蛋白 F     HbF;Hgb F;胎儿血红蛋白
  Dutch (NETHERLANDS)  (From: NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)    
  hemoglobine F      
  Estonian (ESTONIA)  (From: Estonian E-Health Foundation)    
  Hemoglobiin F      
  French (BELGIUM)  (From: Jean M. Prevost, MD, Biopathology)   SYNONYMS
  Hémoglobine F     HbF
  French (CANADA)  (From: Canada Health Infoway Inc.)    
  Hémoglobine F      
  Italian (ITALY)  (From: Consiglio Nazionale delle Ricerche)    
  Emoglobina F      
  Russian (RUSSIAN FEDERATION)  (From: Yaroslavl State Medical Academy)    
  Гемоглобин F      
  Spanish (SPAIN)  (From: the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)   SYNONYMS
  Hemoglobina fetal     Hb F
  Turkish (TURKEY)  (From: LOINC Turkish Translation Group and the Turkish Ministry of Health)    
  Hemoglobin F      

  Detail Page Created On: 6/20/2019 9:35:23 AM
  Display name: Hemoglobin F
  Preferred Abbreviation: Hgb F