LP15900-1     Thyroxine

DESCRIPTION
  Part: Thyroxine
  Description: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosine (monoiodotyrosine) and the coupling of iodotyrosine (diiodotyrosine) in thyroglobulin. Thyroxine is separated from thyroglobulin by proteolysis and released in the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts broad stimulatory effects on cell metabolism.
 
 
  Part: Thyroxine
  Description: Thyroxine (T4) and triiodothyronine (T3), are tyrosine-based hormones produced by the thyroid gland. An important component in the synthesis is iodine. The major form of thyroid hormone in the blood is T4. The ratio of T4 to T3 is roughly 20 to 1. Thyroxine is converted to active T3 (three to four times more potent than T4) within cells by deiodinases (5'-iodinase). These are further processed by decarboxylated and deiodinated to produce iodothyronamine (T1 a) and thyronamine (T0 a).
  Copyright: Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
 
 

BASIC PART PROPERTIES
  Construct for LOINC short name: T4
  Type: COMPONENT
  Status: ACTIVE
  Molecular Wt: 776.874 g/mol
  Created On: 5/4/2000

RELATED CODES
Code System Code Code Text Code Version
   http://pubchem.ncbi.nlm.nih.gov   5819   Thyroxine   

LANGUAGE VARIANTS
 
  Chinese (CHINA)  (From: Lin Zhang, A LOINC volunteer from China)   SYNONYMS
  甲状腺素     T4;T-4;四碘甲状腺原氨酸;四碘甲腺原氨酸;左旋四碘甲状腺原氨酸;左旋四碘甲腺原氨酸;左旋甲状腺氨酸;左旋甲状腺素;左旋甲状腺素(Levothyroxine,Levo-thyroxine,L-thyroxine);甲状腺氨酸
 
  Dutch (NETHERLANDS)  (From: NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)    
  thyroxine      
 
  Estonian (ESTONIA)  (From: Estonian E-Health Foundation)    
  Türoksiin      
 
  French (BELGIUM)  (From: Jean M. Prevost, MD, Biopathology)   SYNONYMS
  Thyroxine     T4
 
  French (CANADA)  (From: Canada Health Infoway Inc.)    
  Thyroxine      
 
  Greek (GREECE)  (From: Efstratia Kontaxi, MD, MSc, and Evripidis Stefanidis, MD, with technical support from Panagiotis Kontaxis, Diploma of Electrical and Computer Engineering.)   SYNONYMS
  Θυροξίνη     Τ4
 
  Italian (ITALY)  (From: Consiglio Nazionale delle Ricerche)    
  Tiroxina      
 
  Russian (RUSSIAN FEDERATION)  (From: Yaroslavl State Medical Academy)    
  Тироксин      
 
  Spanish (SPAIN)  (From: the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)   SYNONYMS
  Tiroxina     Levo-tiroxina
 
  Turkish (TURKEY)  (From: LOINC Turkish Translation Group and the Turkish Ministry of Health)    
  Tiroksin      

INTERNAL FIELDS
  Detail Page Created On: 6/20/2019 9:34:37 AM
  Display name: Thyroxine
  Preferred Abbreviation: T4