LP15429-1     Base excess

DESCRIPTION
  Part: Base excess
  Description: Base excess refers to the amount of a strong acid required to bring back the blood pH to the normal value of 7.4. The term and concept were first introduced by Astrup and Siggaard-Andersen in 1958 as a way to measure the metabolic component of an acid-base disturbance.

Actual versus standard:
In vivo, acid-base homeostasis takes place throughout the extracellular fluid (ECF), not just the blood compartment that is in a patient specimen. The concept of "standard" base excess attempts to adjust for the base excess of the entire extracellular compartment by calculating the base excess for blood diluted as if the entire extracellular compartment were sampled (approx Hgb of 5g/l). So the ACTUAL base excess (ABE) is the dose of acid to return PLASMA to normal pH, whereas the STANDARD base excess (SBE) is the dose to return ECF to normal pH.

Adjusting for oxygen saturation:
Base excess normally assumes 100% oxygen saturation, which is valid for many arterial specimens. However, it is possible to add additional terms to the calculation which account for the actual oxygen saturation of the patient sample. The terms in LOINC indicating 'Base excess.100% oxygenated' are intended to encode base excess terms adjusted for oxygen saturation (i.e. do not assume 100% oxygenation).
 
 

BASIC PART PROPERTIES
  Type: COMPONENT
  Status: ACTIVE
  Created On: 5/4/2000

LANGUAGE VARIANTS
 
  Chinese (CHINA)  (From: Lin Zhang, A LOINC volunteer from China)   SYNONYMS
  碱剩余     BE;BSE;碱超;碱过剩;过剩碱
 
  Dutch (NETHERLANDS)  (From: NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)    
  base-overschot      
 
  Estonian (ESTONIA)  (From: Estonian E-Health Foundation)    
  Aluste liig      
 
  French (BELGIUM)  (From: Jean M. Prevost, MD, Biopathology)    
  Excès de base      
 
  French (CANADA)  (From: Canada Health Infoway Inc.)    
  Excès de base      
 
  Italian (ITALY)  (From: Consiglio Nazionale delle Ricerche)   SYNONYMS
  Basi, eccesso     Eccesso di basi
 
  Russian (RUSSIAN FEDERATION)  (From: Yaroslavl State Medical Academy)    
  Оснований избыток      
 
  Spanish (SPAIN)  (From: the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)    
  Exceso de base      
 
  Turkish (TURKEY)  (From: LOINC Turkish Translation Group and the Turkish Ministry of Health)    
  Baz fazlalığı      

INTERNAL FIELDS
  Detail Page Created On: 6/20/2019 9:32:52 AM
  Display name: Base excess
  Preferred Abbreviation: Base excess