LP14853-3     Varicella zoster virus

DESCRIPTION
  Part: Varicella zoster virus
  Description: Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3—represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5—found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2—Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/
 
 

BASIC PART PROPERTIES
  Construct for LOINC short name: VZV
  Type: COMPONENT
  Status: ACTIVE
  Created On: 5/4/2000

LANGUAGE VARIANTS
 
  Chinese (CHINA)  (From: Lin Zhang, A LOINC volunteer from China)   SYNONYMS
  水痘带状疱疹病毒     HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒
 
  Dutch (NETHERLANDS)  (From: NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)   SYNONYMS
  varicella-zostervirus     Varicella zoster virus
 
  Estonian (ESTONIA)  (From: Estonian E-Health Foundation)    
  Tuulerõugeviirus      
 
  French (BELGIUM)  (From: Jean M. Prevost, MD, Biopathology)   SYNONYMS
  Virus varicelle-zona     VZV
 
  French (CANADA)  (From: Canada Health Infoway Inc.)    
  Virus varicelle-zona      
 
  Greek (GREECE)  (From: Efstratia Kontaxi, MD, MSc, and Evripidis Stefanidis, MD, with technical support from Panagiotis Kontaxis, Diploma of Electrical and Computer Engineering.)   SYNONYMS
  Ιός ανεμευλογιάς-έρπητα ζωστήρα     VZV
 
  Italian (ITALY)  (From: Consiglio Nazionale delle Ricerche)   SYNONYMS
  Varicella zoster, virus     Virus della varicella zoster
 
  Russian (RUSSIAN FEDERATION)  (From: Yaroslavl State Medical Academy)    
  Varicella zoster вирус      
 
  Spanish (SPAIN)  (From: the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)   SYNONYMS
  Virus Varicella zoster     Herpes Varicela
 
  Turkish (TURKEY)  (From: LOINC Turkish Translation Group and the Turkish Ministry of Health)    
  Varicella zoster virüsü      

INTERNAL FIELDS
  Detail Page Created On: 6/20/2019 9:31:03 AM
  Display name: Varicella zoster virus
  Preferred Abbreviation: VZV