LP14729-5     PHENobarbital

DESCRIPTION
  Part: PHENobarbital
  Description: Phenobarbital is an antiepileptic drug first introduced for clinical use in 1912. It is still used to treat most seizures except for absence seizure types. The CYP2C19 enzyme metabolizes phenobarbital to p-hydroxyphenobarbital which is then excreted as glucuronide. Phenobarbital induces secretion of liver enzymes which can impact the efficacy of drugs administered at the same time. The most common side effect of phenobarbital in adults with blood levels greater than 40 mg/L is sedation. Phenobarbital is an active metabolite of primidone and so must also be monitored in patients on primidone.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns)
 
 

BASIC PART PROPERTIES
  Construct for LOINC short name: PHENobarb
  Type: COMPONENT
  Status: ACTIVE
  Created On: 5/4/2000

RELATED CODES
Code System Code Code Text Code Version
   http://www.nlm.nih.gov/research/umls/rxnorm   8134   Phenobarbital   

LANGUAGE VARIANTS
 
  Chinese (CHINA)  (From: Lin Zhang, A LOINC volunteer from China)   SYNONYMS
  苯巴比妥     C12H12N2O3;苯巴比妥米那;鲁米那;苯基巴比妥;本巴比妥
 
  Dutch (NETHERLANDS)  (From: NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)    
  fenobarbital      
 
  Estonian (ESTONIA)  (From: Estonian E-Health Foundation)    
  Fenobarbitaal      
 
  French (BELGIUM)  (From: Jean M. Prevost, MD, Biopathology)    
  Phénobarbital      
 
  French (CANADA)  (From: Canada Health Infoway Inc.)    
  Phénobarbital      
 
  Greek (GREECE)  (From: Efstratia Kontaxi, MD, MSc, and Evripidis Stefanidis, MD, with technical support from Panagiotis Kontaxis, Diploma of Electrical and Computer Engineering.)    
  Φαινοβαρβιτάλη      
 
  Italian (ITALY)  (From: Consiglio Nazionale delle Ricerche)    
  Fenobarbital      
 
  Russian (RUSSIAN FEDERATION)  (From: Yaroslavl State Medical Academy)    
  Фенобарбитал      
 
  Spanish (SPAIN)  (From: the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)   SYNONYMS
  Fenobarbital     Luminal
 
  Turkish (TURKEY)  (From: LOINC Turkish Translation Group and the Turkish Ministry of Health)    
  Fenobarbital      

INTERNAL FIELDS
  Detail Page Created On: 6/20/2019 9:29:30 AM
  Display name: PHENobarbital
  Preferred Abbreviation: PHENobarb