75545-4  Genetic counselor comment on overall fetal aneuploidy and microdeletion risk [Text] based on Plasma cell-free+​WBC DNAGenetic counselor comment on overall fetal aneuploidy and microdeletion risk [Text] based on Plasma cell-free+​WBC DNAGenetic counselor comment on overall fetal aneuploidy and microdeletion risk: Txt: Pt: WBC.DNA+​Plas.cfDNA: Nar:  

NAME
  Fully Specified Name: 
Component   Property   Time   System   Scale   Method
Genetic counselor comment on overall fetal aneuploidy and microdeletion risk  Txt  Pt  WBC.DNA+Plas.cfDNA  Nar 
  Long Common Name:  Genetic counselor comment on overall fetal aneuploidy and microdeletion risk [Text] based on Plasma cell-free+WBC DNA
  Short Name:  Genetic couns comm fet aneu microdel rsk
  Display Name:  Genetic counselor comment on overall fetal aneuploidy and microdel risk Nar (Plasma cell-free+WBC DNA)

TERM DEFINITION/DESCRIPTION(S)
  This term was developed for, but is not limited in use to, Natera's Panorama noninvasive prenatal test for fetal aneuploidies and microdeletions.
 
 

PART DEFINITION/DESCRIPTION(S)
  Part: Genetic counselor comment on overall fetal aneuploidy and microdeletion risk
  Noninvasive prenatal screening is used to assess fetal risk for various genetic conditions without requiring invasive maternal procedures such as amniocentesis or chorionic villus sampling. Cell-free DNA (cfDNA) in maternal plasma comes from both fetal and maternal sources, and various platforms have been developed using cfDNA to determine fetal risk. Natera's Panorama prenatal screening test uses a single blood sample from a pregnant woman, and using their proprietary informatics analysis method (NATUS), effectively subtracts the maternal genotype (from WBC DNA) from the cfDNA genotype and analyzes the remaining fetal cfDNA genotype for a variety of conditions including aneuploidy (e.g., Trisomy 21, Monosomy X) and microdeletions (e.g., 22q11.2 deletion). Specific results are typically reported for each individual condition and summarized for the report as a whole -- if the risk of any individual condition is high, the overall interpretation is "high risk," and if all the individual risks are low, the overall interpretation is "low risk." In addition, the genetic counselor who reviews the results may add specific interpretation details or follow-up recommendations to the report.
 
 

BASIC ATTRIBUTES
  Class/Type: MOLPATH/Lab
  Common Lab Results Rank: #3000
  Common SI Lab Results Rank: #3000
  First Released in Version: 2.50
  Last Updated in Version: 2.54
  Order vs. Obs.: Observation
  Status: Active

MEMBER OF THESE PANELS     
  This section provides information about panels that contain this LOINC code.
  LOINC   Long Common Name  
  75547-0 Noninvasive prenatal fetal aneuploidy and microdeletion panel based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific circulating cell free (ccf) DNA
  

PARTS

Part Type    Part No.  Part Name   
Component   LP185985-1  Genetic counselor comment on overall fetal aneuploidy and microdeletion risk 
Property   LP6885-0  Txt   [Text] 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP185797-0  WBC.DNA+Plas.cfDNA   [Plasma cell-free+WBC DNA] 
Scale   LP7749-7  Nar 
Fragments for synonyms   LP20987-1  Comment 
Fragments for synonyms   LP247965-9  Genetic 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  关于胎儿非整倍体性与染色体微缺失总体风险的遗传咨询师意见:文本型属性:时间点:白细胞.DNA+​血浆.cfDNA:叙述型:关于胎儿非整倍体性与染色体微缺失总体风险的遗传咨询师意见:文本型属性:时间点:白细胞.DNA+​血浆.cfDNA:叙述型:
  French (FRANCE)  (From: ASIP Santé (Agence des systèmes d'information partagés de santé))
 
  Genetic counselor comment on overall fetal aneuploidy and microdeletion risk:Txt:Pt:WBC.DNA+​Plas.cfDNA:Nar:Genetic counselor comment on overall fetal aneuploidy and microdeletion risk:Txt:Pt:WBC.DNA+​Plas.cfDNA:Nar:Risque d'aneuploïdie et microdélétion foetale commentaire du conseiller génétique [Texte] Leucocytes ADN+​Plasma avec ADN libre circulant ; Résultat textuel
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Commento di consulente genetico su rischio generale microdelezione e aneuploidaia fetale:Txt:Pt:WBC.DNA+​Plas.cfDNA:Nar:Commento di consulente genetico su rischio generale microdelezione e aneuploidaia fetale:Txt:Pt:WBC.DNA+​Plas.cfDNA:Nar:
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Comentario de consejo genético en el riesgo general de aneuploidía fetal y microdeleción:Texto:Punto temporal:ADN en plasma libre de células y leucocitos:Narrativo:Comentario de consejo genético en el riesgo general de aneuploidía fetal y microdeleción:Texto:Punto temporal:ADN en plasma libre de células y leucocitos:Narrativo:
  Turkish (TURKEY)  (From: Regenstrief-generated full translation based on part translation provided by LOINC Turkish Translation Group and the Turkish Ministry of Health)
 
  Tüm fetal aneuploidi ve mikrodelesyon riski genetik danışman önerisi:Metin:Zmlı:WBC.DNA+​Plaz.cfDNA:Öykü:Tüm fetal aneuploidi ve mikrodelesyon riski genetik danışman önerisi:Metin:Zmlı:WBC.DNA+​Plaz.cfDNA:Öykü:

RELATED NAMES
  cmmt Leukocytes Remarks
  cmnt Molecular pathology Report
  Com MOLPATH Text
  Comm Narrative WBC.DNA+cfDNA
  Comments Pl WBCs
  Commt Plasma White blood cells
  Gen couns comm aneu microdel risk Plsm  
  Genetics Point in time  
  Genomic Random  

CHANGE HISTORY
  Change Type: MIN

INTERNAL FIELDS
  Detail Page Created On: 6/26/2019 2:43:28 PM
  Long Common Name: Genetic counselor comment on overall fetal aneuploidy and microdeletion risk [Text] based on Plasma cell-free+WBC DNA
  Shortname: Genetic couns comm fet aneu microdel rsk
  Fully Specified Name: Genetic counselor comment on overall fetal aneuploidy and microdeletion risk: Txt: Pt: WBC.DNA+Plas.cfDNA: Nar:
     
  Component Word Count: 10
  ID: 77233
  Status (Raw): ACTIVE