49575-4  Sphingomyelin/​Surfactant.total in Amniotic fluidSphingomyelin/​Surfactant.total in Amniotic fluidSphingomyelin/​Surfactant.total: MFr: Pt: Amnio fld: Qn:  

NAME
  Fully Specified Name: 
Component   Property   Time   System   Scale   Method
Sphingomyelin/Surfactant.total  MFr  Pt  Amnio fld  Qn 
  Long Common Name:  Sphingomyelin/Surfactant.total in Amniotic fluid
  Short Name:  Sphingomyelin MFr Amn
  Display Name:  Sphingomyelin/Surfactant.total (Amn fld) [Mass fraction]

PART DEFINITION/DESCRIPTION(S)
  Part: Sphingomyelin
  Sphingomyelin (SPH) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath that surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans SPH represents ~85% of all sphingolipids.

Sphingomyelin can accumulate in a rare hereditary disease called Niemann-Pick Disease, types A and B. It is a genetically-inherited disease caused by a deficiency in the enzyme Sphingomyelinase, which causes the accumulation of Sphingomyelin in spleen, liver, lungs, bone marrow, and the brain, causing irreversible neurological damage. Of the two types involving Sphingomyelinase, type A occurs in infants. It is characterized by jaundice, an enlarged liver, and profound brain damage. Children with this type rarely live beyond 18 months. Type B involves an enlarged liver and spleen, which usually occurs in the pre-teen years. The brain is not affected. Most patients present with <1% normal levels of the enzyme in comparison to normal levels.

An excess of spingomyelin in the red blood cell membrane (as in abetalipoproteinemia) causes excess lipid accumulation in the outer leaflet of the red blood cell plasma membrane. This results in abnormally shaped red cells called acanthocytes.
  Copyright: Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
 
 

BASIC ATTRIBUTES
  Class/Type: CHEM/Lab
  First Released in Version: 2.22
  Last Updated in Version: 2.30
  Order vs. Obs.: Both
  Status: Active

SUBMITTER'S INFORMATION
  Submitted Units: %

MEMBER OF THESE PANELS     
  This section provides information about panels that contain this LOINC code.
  LOINC   Long Common Name  
  50009-0 Fetal lung maturity panel - Amniotic fluid
  

PARTS

Part Type    Part No.  Part Name   
Component   LP15698-1  Sphingomyelin 
     Divisors   LP32161-9  Surfactant.total 
Property   LP6831-4  MFr   [Mass fraction] 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP7000-5  Amnio fld   [Amniotic fluid] 
Scale   LP7753-9  Qn 
Fragments for synonyms   LP21089-5  Total 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  神经鞘磷脂/​表面活性物质.总计:质量分数:时间点:羊水:定量型:神经鞘磷脂/​表面活性物质.总计:质量分数:时间点:羊水:定量型:
  Dutch (NETHERLANDS)  (From: Regenstrief-generated full translation based on part translation provided by NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)
 
  sfingomyeline/​surfactant.totaal:massafractie:moment:vruchtwater:kwantitatief:sfingomyeline/​surfactant.totaal:massafractie:moment:vruchtwater:kwantitatief:
  Estonian (ESTONIA)  (From: Regenstrief-generated full translation based on part translation provided by Estonian E-Health Foundation)
 
  Sfingomüeliin/​surfaktant.üld:MFr:Pt:AmnF:Qn:Sfingomüeliin/​surfaktant.üld:MFr:Pt:AmnF:Qn:
  French (BELGIUM)  (From: Regenstrief-generated full translation based on part translation provided by Jean M. Prevost, MD, Biopathology)
 
  Sphingomyéline/​Surfactant.total:Fraction de masse:Temps ponctuel:Liquide amniotique:Quantitatif:Sphingomyéline/​Surfactant.total:Fraction de masse:Temps ponctuel:Liquide amniotique:Quantitatif:
  French (CANADA)  (From: Regenstrief-generated full translation based on part translation provided by Canada Health Infoway Inc.)
 
  Sphingomyéline/​Surfactant.total:Fraction de masse:Temps ponctuel:Liquide amniotique:Quantitatif:Sphingomyéline/​Surfactant.total:Fraction de masse:Temps ponctuel:Liquide amniotique:Quantitatif:
  French (FRANCE)  (From: ASIP Santé (Agence des systèmes d'information partagés de santé))
 
  Sphingomyelin/​Surfactant.total:MFr:Pt:Amnio fld:Qn:Sphingomyelin/​Surfactant.total:MFr:Pt:Amnio fld:Qn:Sphingomyéline/​surfactant total [Fraction massique] Liquide amniotique ; Numérique
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Sfingomielina/​Surfattante totale:MFr:Pt:Liquido amniotico:Qn:Sfingomielina/​Surfattante totale:MFr:Pt:Liquido amniotico:Qn:
  Portuguese (BRAZIL)  (From: HL7 Brazil Institute)
 
  Esfingomielina/​Surfactante.total:MFr:Pt:LiqAmni:Qn:Esfingomielina/​Surfactante.total:MFr:Pt:LiqAmni:Qn:
  Russian (RUSSIAN FEDERATION)  (From: Regenstrief-generated full translation based on part translation provided by Yaroslavl State Medical Academy)
 
  Сфингомиелин/​Сурфактант.общий:МассДол:ТчкВрм:Амниотич ждк:Колич:Сфингомиелин/​Сурфактант.общий:МассДол:ТчкВрм:Амниотич ждк:Колич:
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Esfingomielina/​Surfactante.total:Fracción de masa:Punto temporal:Fluido Ammiótico:Qn:Esfingomielina/​Surfactante.total:Fracción de masa:Punto temporal:Fluido Ammiótico:Qn:
  Turkish (TURKEY)  (From: Regenstrief-generated full translation based on part translation provided by LOINC Turkish Translation Group and the Turkish Ministry of Health)
 
  Sfingomiyelin/​Sürfaktan.total:KütlFr:Zmlı:Amniyon sv:Kant:Sfingomiyelin/​Sürfaktan.total:KütlFr:Zmlı:Amniyon sv:Kant:

RELATED NAMES
  AF Mass Fraction Random
  Amn Percent SPH
  Amn fl Point in time Tot
  Amnio QNT Totl
  Amniotic flu Quan  
  Amniotic fluid Quant  
  Chemistry Quantitative  

EXAMPLE UNITS
  Unit  Source Type
  EXAMPLE UCUM UNITS 
  ORIGINAL SUBMISSION 
  REGENSTRIEF 

UNITS (INTERNAL DETAILS)
  Source Type:  EXAMPLE UCUM UNITS 
  Unit: 
  Source Type:  ORIGINAL SUBMISSION 
  Unit: 
  Source Type:  REGENSTRIEF 
  Unit: 

CHANGE HISTORY
  Change Type: MIN

INTERNAL FIELDS
  Detail Page Created On: 6/26/2019 5:14:26 PM
  Attachment Units Required: N
  Long Common Name: Sphingomyelin/Surfactant.total in Amniotic fluid
  Shortname: Sphingomyelin MFr Amn
  Fully Specified Name: Sphingomyelin/Surfactant.total: MFr: Pt: Amnio fld: Qn:
     
  Component Word Count: 3
  ID: 43335
  Status (Raw): ACTIVE