47363-7  Cytomegalovirus Ab [Presence] in Serum from Donor by HemagglutinationCytomegalovirus Ab [Presence] in Serum from Donor by HemagglutinationCytomegalovirus Ab: PrThr: Pt: Ser^Donor: Ord: HA  

NAME
  Fully Specified Name: 
Component   Property   Time   System   Scale   Method
Cytomegalovirus Ab  PrThr  Pt  Ser^Donor  Ord  HA
  Long Common Name:  Cytomegalovirus Ab [Presence] in Serum from Donor by Hemagglutination
  Short Name:  CMV Ab Ser Donr Ql HA
  Display Name:  CMV Ab HA Ql (S donor)

TERM DEFINITION/DESCRIPTION(S)
  This test is intended to be used as a primary screening test for the diagnosis of infection with Cytomegalovirus (CMV). This test has been approved by the FDA for the screening of donors of human cells, tissues and tissue-based products. A Positive result is indicative of an infection with CMV, and may be used to disqualify a potential cell or tissue donor. This test is not intended to be used for routine clinical diagnostic testing. This test is required for all donors of "leukocyte-rich" human cells, tissues and tissue-based products
 
 

PART DEFINITION/DESCRIPTION(S)
  Part: Cytomegalovirus
  Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
 
 

BASIC ATTRIBUTES
  Class/Type: MICRO/Lab
  First Released in Version: 2.19
  Last Updated in Version: 2.56
  Order vs. Obs.: Both
  Status: Active.
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

EXAMPLE ANSWER LIST    (LL360-9)  
 
Source: Regenstrief Institute
  SEQ#        Answer        Answer ID    
  1       Positive
http://snomed.info/sct ©: 10828004 Positive (qualifier value)    
  LA6576-8  
  2       Negative
http://snomed.info/sct ©: 260385009 Negative (qualifier value)    
  LA6577-6  

EXAMPLE ANSWERS
  Negative

MEMBER OF THESE PANELS     
  This section provides information about panels that contain this LOINC code.
  LOINC   Long Common Name  
  54037-7 HEDIS 2009 panel
  57820-3 HEDIS 2010 panel
  60442-1 HEDIS 2011 panel
  67767-4 HEDIS 2012 panel
  72199-3 HEDIS 2013 panel
  74234-6 HEDIS 2014 Value Sets
  75868-0 HEDIS 2015 Value Sets
  79544-3 HEDIS 2016 Value Sets
  82955-6 HEDIS 2017 Value Sets
  87625-0 HEDIS 2018 Value Sets
  

PARTS

Part Type    Part No.  Part Name   
Component   LP14255-1  Cytomegalovirus 
Component   LP37878-3  Cytomegalovirus Ab 
     Suffix   LP20667-9  Ab 
Property   LP217195-9  PrThr   [Presence or Threshold] 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP7567-3  Ser   [Serum] 
     Super System   LP7742-2  Donor 
Scale   LP7751-3  Ord 
Method   LP28800-8  HA   [Hemagglutination] 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  巨细胞病毒 抗体:存在情况或阈值:时间点:血清^供体:序数型:红细胞凝集试验法巨细胞病毒 抗体:存在情况或阈值:时间点:血清^供体:序数型:红细胞凝集试验法
  Dutch (NETHERLANDS)  (From: Regenstrief-generated full translation based on part translation provided by NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)
 
  Cytomegalovirus As:aanwezigheid:moment:serum^donor:ordinaal:hemagglutinatieCytomegalovirus As:aanwezigheid:moment:serum^donor:ordinaal:hemagglutinatie
  Estonian (ESTONIA)  (From: Regenstrief-generated full translation based on part translation provided by Estonian E-Health Foundation)
 
  Tsütomegaloviirus antikehad:PrThr:Pt:S^doonor:Ord:HATsütomegaloviirus antikehad:PrThr:Pt:S^doonor:Ord:HA
  French (BELGIUM)  (From: Regenstrief-generated full translation based on part translation provided by Jean M. Prevost, MD, Biopathology)
 
  Cytomégalovirus Ac:PrThr:Temps ponctuel:Sérum^Donneur:Ordinal:HémagglutinationCytomégalovirus Ac:PrThr:Temps ponctuel:Sérum^Donneur:Ordinal:Hémagglutination
  French (CANADA)  (From: Regenstrief-generated full translation based on part translation provided by Canada Health Infoway Inc.)
 
  Cytomégalovirus , Ac:Présence-Seuil:Temps ponctuel:Sérum^Donneur:Ordinal:HémagglutinationCytomégalovirus , Ac:Présence-Seuil:Temps ponctuel:Sérum^Donneur:Ordinal:Hémagglutination
  French (FRANCE)  (From: ASIP Santé (Agence des systèmes d'information partagés de santé))
 
  Cytomegalovirus Ab:PrThr:Pt:Ser^Donor:Ord:HACytomegalovirus Ab:PrThr:Pt:Ser^Donor:Ord:HACytomégalovirus Ac [Présence/​Seuil] Sérum du donneur ; Qualitatif ; Hémagglutination
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Citomegalovirus , Ab:PrThr:Pt:Siero^donatore:Ord:HACitomegalovirus , Ab:PrThr:Pt:Siero^donatore:Ord:HA
  Portuguese (BRAZIL)  (From: HL7 Brazil Institute)
 
  Citomegalovírus Ac:ACnc:Pt:Soro^doador:Ord:HemaglutinaçãoCitomegalovírus Ac:ACnc:Pt:Soro^doador:Ord:Hemaglutinação
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Citomegalovirus Anticuerpos:PrThr:Punto temporal:Suero^donante:Ord:HemaglutinacionCitomegalovirus Anticuerpos:PrThr:Punto temporal:Suero^donante:Ord:Hemaglutinacion
  Turkish (TURKEY)  (From: Regenstrief-generated full translation based on part translation provided by LOINC Turkish Translation Group and the Turkish Ministry of Health)
 
  Cytomegalovirus Ab:MevcEşik:Zmlı:Ser^verici:Srl:HACytomegalovirus Ab:MevcEşik:Zmlı:Ser^verici:Srl:HA

RELATED NAMES
  ABS Cytomgal QL
  Aby Donr Qual
  Antby Hemagglutination Qualitative
  Anti HHV-5 Random
  Antibodies Human Herpesvirus-5 Screen
  Antibody IHA Serum
  Autoantibodies Microbiology SR
  Autoantibody Ordinal  
  CMV Point in time  
  Cytomegalo virus PR  

CHANGE HISTORY
  Change Type: MAJ

INTERNAL FIELDS
  Detail Page Created On: 6/26/2019 5:24:48 PM
  Attachment Units Required: N
  Long Common Name: Cytomegalovirus Ab [Presence] in Serum from Donor by Hemagglutination
  Shortname: CMV Ab Ser Donr Ql HA
  Fully Specified Name: Cytomegalovirus Ab: PrThr: Pt: Ser^Donor: Ord: HA
     
  Component Word Count: 2
  ID: 40891
  Status (Raw): ACTIVE

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  Code System: http://snomed.info/sct
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