45326-6  Cytomegalovirus IgG Ab avidity [Ratio] in Serum or PlasmaCytomegalovirus IgG Ab avidity [Ratio] in Serum or PlasmaCytomegalovirus Ab.IgG avidity: Ratio: Pt: Ser/​Plas: Qn: Map To: 52984-2 

NAME
  Fully Specified Name: 
Component   Property   Time   System   Scale   Method
Cytomegalovirus Ab.IgG avidity  Ratio  Pt  Ser/Plas  Qn 
  Long Common Name:  Cytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma
  Short Name:  CMV IgG Avidity SerPl-Rto
  Display Name:  CMV IgG avidity [Ratio]

PART DEFINITION/DESCRIPTION(S)
  Part: Cytomegalovirus
  Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
 
 

BASIC ATTRIBUTES
  Class/Type: MICRO/Lab
  First Released in Version: 2.17
  Last Updated in Version: 2.64
  Order vs. Obs.: Both
  Status: Discourage use.
Change Reason: Updated System from Ser to Ser/Plas since this test can also be done on plasma.
Reason for status: Suggest using method specific term. Replace with LOINC # 52984-2: Cytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma by ImmunoassayCytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma by ImmunoassayCytomegalovirus Ab.IgG avidity: Ratio: Pt: Ser/​Plas: Qn: IA

MEMBER OF THESE PANELS     
  This section provides information about panels that contain this LOINC code.
  LOINC   Long Common Name  
  54037-7 HEDIS 2009 panel
  57820-3 HEDIS 2010 panel
  60442-1 HEDIS 2011 panel
  67767-4 HEDIS 2012 panel
  72199-3 HEDIS 2013 panel
  74234-6 HEDIS 2014 Value Sets
  75868-0 HEDIS 2015 Value Sets
  79544-3 HEDIS 2016 Value Sets
  82955-6 HEDIS 2017 Value Sets
  87625-0 HEDIS 2018 Value Sets
  90766-7 HEDIS 2019 Value Sets
  

PARTS

Part Type    Part No.  Part Name   
Component   LP40408-4  Cytomegalovirus Ab.IgG avidity   [Cytomegalovirus IgG Avidity] 
Component   LP14255-1  Cytomegalovirus 
     Suffix   LP32413-4  Ab.IgG avidity   [IgG Avidity] 
Property   LP6852-0  Ratio 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP7576-4  Ser/Plas   [Serum or Plasma] 
Scale   LP7753-9  Qn 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  巨细胞病毒 抗体.IgG 亲合力:比率:时间点:血清/​血浆:定量型:巨细胞病毒 抗体.IgG 亲合力:比率:时间点:血清/​血浆:定量型:
  Dutch (NETHERLANDS)  (From: Regenstrief-generated full translation based on part translation provided by NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)
 
  Cytomegalovirus As.IgG-aviditeit:verhouding:moment:serum of plasma:kwantitatief:Cytomegalovirus As.IgG-aviditeit:verhouding:moment:serum of plasma:kwantitatief:
  Estonian (ESTONIA)  (From: Regenstrief-generated full translation based on part translation provided by Estonian E-Health Foundation)
 
  Tsütomegaloviirus antikehad.IgG aviidsus:Suhe:Pt:S/​P:Qn:Tsütomegaloviirus antikehad.IgG aviidsus:Suhe:Pt:S/​P:Qn:
  French (BELGIUM)  (From: Regenstrief-generated full translation based on part translation provided by Jean M. Prevost, MD, Biopathology)
 
  Cytomégalovirus Anticorps.avidité des IgG:Ratios:Temps ponctuel:Sérum/​Plasma:Quantitatif:Cytomégalovirus Anticorps.avidité des IgG:Ratios:Temps ponctuel:Sérum/​Plasma:Quantitatif:
  French (CANADA)  (From: Regenstrief-generated full translation based on part translation provided by Canada Health Infoway Inc.)
 
  Cytomégalovirus , Ac.avidité des IgG:Ratios:Temps ponctuel:Sérum/​Plasma:Quantitatif:Cytomégalovirus , Ac.avidité des IgG:Ratios:Temps ponctuel:Sérum/​Plasma:Quantitatif:
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Citomegalovirus , Ab.avidità IgG:Rapporto:Pt:Siero/​Plasma:Qn:Citomegalovirus , Ab.avidità IgG:Rapporto:Pt:Siero/​Plasma:Qn:
  Portuguese (BRAZIL)  (From: HL7 Brazil Institute)
 
  Citomegalovírus Ac.IgG avidez:ACnc:Pt:Soro:Qn:Citomegalovírus Ac.IgG avidez:ACnc:Pt:Soro:Qn:
  Russian (RUSSIAN FEDERATION)  (From: Regenstrief-generated full translation based on part translation provided by Yaroslavl State Medical Academy)
 
  Цитомегаловирус Ат.IgG авидность:Отношение:ТчкВрм:Сыв/​Плаз:Колич:Цитомегаловирус Ат.IgG авидность:Отношение:ТчкВрм:Сыв/​Плаз:Колич:
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Citomegalovirus Avidez IgG:Fracción:Punto temporal:Suero o Plasma:Qn:Citomegalovirus Avidez IgG:Fracción:Punto temporal:Suero o Plasma:Qn:
  Turkish (TURKEY)  (From: Regenstrief-generated full translation based on part translation provided by LOINC Turkish Translation Group and the Turkish Ministry of Health)
 
  Cytomegalovirus Ab.IgG avidite:Oran:Zmlı:Ser/​Plaz:Kant:Cytomegalovirus Ab.IgG avidite:Oran:Zmlı:Ser/​Plaz:Kant:

RELATED NAMES
  ABS Human Herpesvirus-5 Random
  Aby Immune globulin G Ratios
  Antby Immunoglobulin G Rto
  Anti Microbiology SerP
  Antibodies Pl SerPl
  Antibody Plasma SerPlas
  Autoantibodies Plsm Serum
  Autoantibody Point in time Serum or plasma
  CMV QNT SR
  Cytomegalo virus Quan  
  Cytomgal Quant  
  HHV-5 Quantitative  

CHANGE HISTORY
  Change Type: MAJ

INTERNAL FIELDS
  Detail Page Created On: 6/26/2019 5:37:15 PM
  Attachment Units Required: N
  Long Common Name: Cytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma
  Shortname: CMV IgG Avidity SerPl-Rto
  Fully Specified Name: Cytomegalovirus Ab.IgG avidity: Ratio: Pt: Ser/Plas: Qn:
     
  Component Word Count: 4
  ID: 38667
  Status (Raw): DISCOURAGED