36903-3  Chlamydia trachomatis and Neisseria gonorrhoeae DNA [Identifier] in Unspecified specimen by NAA with probe detectionChlamydia trachomatis and Neisseria gonorrhoeae DNA [Identifier] in Unspecified specimen by NAA with probe detectionChlamydia trachomatis & Neisseria gonorrhoeae DNA: Prid: Pt: XXX: Nom: Probe.amp.tar  

NAME
  Fully Specified Name: 
Component   Property   Time   System   Scale   Method
Chlamydia trachomatis & Neisseria gonorrhoeae DNA  Prid  Pt  XXX  Nom  Probe.amp.tar
  Long Common Name:  Chlamydia trachomatis and Neisseria gonorrhoeae DNA [Identifier] in Unspecified specimen by NAA with probe detection
  Short Name:  C trach+GC DNA XXX NAA+probe
  Display Name:  C. trachomatis and N. gonorrhoeae DNA NAA+probe Nom (Unsp spec)

PART DEFINITION/DESCRIPTION(S)
  Part: Chlamydia trachomatis & Neisseria gonorrhoeae
  Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the “flasher” kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the “glower” kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type.
 
 

BASIC ATTRIBUTES
  Class/Type: MICRO/Lab
  Common Lab Results Rank: #327
  Common SI Lab Results Rank: #327
  First Released in Version: 2.13
  Last Updated in Version: 2.63
  Order vs. Obs.: Both
  Status: Active.
Change Reason: Changed + to & in Component because this is a Prid/Nom term that is used for assays that can detect and differentiate between the organisms.

EXAMPLE ANSWER LIST    (LL1501-7)  
 
Source: Association of Public Health Laboratories
  SEQ#        Answer        Answer ID    
  1       Chlamydia trachomatis detected       LA16153-1  
  2       Chlamydia trachomatis not detected       LA16154-9  
  3       Chlamydia trachomatis inconclusive       LA16155-6  
  4       Chlamydia trachomatis equivocal       LA16157-2  
  5       Neisseria gonorrhoeae detected       LA16150-7  
  6       Neisseria gonorrhoeae not detected       LA16151-5  
  7       Neisseria gonorrhoeae inconclusive       LA16152-3  
  8       Neisseria gonorrhoeae equivocal       LA16156-4  

EXAMPLE ANSWERS
  Chlamydia trachomatis detected Neisseria gonorrhoeae detected No Chlamydia trachomatis detected  
  Chlamydia trachomatis detected No Neisseria gonorrhoeae detected No Chlamydia trachomatis detected No Neisseria gonorrhoeae detected  
  Neisseria gonorrhoeae detected    

MEMBER OF THESE PANELS     
  This section provides information about panels that contain this LOINC code.
  LOINC   Long Common Name  
  54037-7 HEDIS 2009 panel
  57820-3 HEDIS 2010 panel
  60442-1 HEDIS 2011 panel
  67767-4 HEDIS 2012 panel
  72199-3 HEDIS 2013 panel
  74234-6 HEDIS 2014 Value Sets
  75868-0 HEDIS 2015 Value Sets
  79544-3 HEDIS 2016 Value Sets
  82955-6 HEDIS 2017 Value Sets
  86636-8 Family planning report - FPAR 2.0 set
  87625-0 HEDIS 2018 Value Sets
  90766-7 HEDIS 2019 Value Sets
  

PARTS

Part Type    Part No.  Part Name   
Component   LP115359-4  Chlamydia trachomatis & Neisseria gonorrhoeae   [Chlamydia trachomatis and Neisseria gonorrhoeae] 
Component   LP157729-7  Chlamydia trachomatis & Neisseria gonorrhoeae DNA   [Chlamydia trachomatis and Neisseria gonorrhoeae DNA] 
     Suffix   LP32416-7  DNA 
Property   LP6850-4  Prid   [Presence or Identity] 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP7735-6  XXX 
Scale   LP7750-5  Nom 
Method   LP6464-4  Probe.amp.tar   [Nucleic acid amplification with probe detection] 
Fragments for synonyms   LP20682-8  Chlamydia 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  沙眼衣原体与淋病奈瑟菌 DNA:存在与否或特征标识:时间点:XXX:名义型:探针法.基因扩增.靶向沙眼衣原体与淋病奈瑟菌 DNA:存在与否或特征标识:时间点:XXX:名义型:探针法.基因扩增.靶向
  Dutch (NETHERLANDS)  (From: Regenstrief-generated full translation based on part translation provided by NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)
 
  Chlamydia trachomatis & Neisseria gonorrhoeae DNA:identificator:moment:XXX:nominaal:moleculaire techniek (PCR)Chlamydia trachomatis & Neisseria gonorrhoeae DNA:identificator:moment:XXX:nominaal:moleculaire techniek (PCR)
  French (CANADA)  (From: Regenstrief-generated full translation based on part translation provided by Canada Health Infoway Inc.)
 
  Chlamydia trachomatis & Neisseria gonorrhoeae , ADN:Présence ou identité:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cibleChlamydia trachomatis & Neisseria gonorrhoeae , ADN:Présence ou identité:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cible
  French (FRANCE)  (From: ASIP Santé (Agence des systèmes d'information partagés de santé))
 
  Chlamydia trachomatis & Neisseria gonorrhoeae DNA:Prid:Pt:XXX:Nom:Probe.amp.tarChlamydia trachomatis & Neisseria gonorrhoeae DNA:Prid:Pt:XXX:Nom:Probe.amp.tarChlamydia trachomatis et Neisseria gonorrhoeae ADN [Identification] Milieux divers ; Résultat nominal ; PCR amplification de cible
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Chlamydia trachomatis & Neisseria gonorrhoeae , DNA:Prid:Pt:XXX:Nom:Sonda.amp.tarChlamydia trachomatis & Neisseria gonorrhoeae , DNA:Prid:Pt:XXX:Nom:Sonda.amp.tar
  Korean (KOREA, REPUBLIC OF)  (From: Korean Ministry for Health, Welfare, and Family Affairs)
 
  클라미디아 트라코마티스+​임균 디옥시리보핵산:존재:검사시점:XXX:명칭결과:DNA 탐색자.증폭.표적클라미디아 트라코마티스+​임균 디옥시리보핵산:존재:검사시점:XXX:명칭결과:DNA 탐색자.증폭.표적
  Portuguese (BRAZIL)  (From: HL7 Brazil Institute)
 
  Chlamydia trachomatis+​Neisseria gonorrhoeae DNA:Ident:Pt:XXX:Nom:Sonda com limite de detecção da amplificação de alvoChlamydia trachomatis+​Neisseria gonorrhoeae DNA:Ident:Pt:XXX:Nom:Sonda com limite de detecção da amplificação de alvo
  Russian (RUSSIAN FEDERATION)  (From: Regenstrief-generated full translation based on part translation provided by Yaroslavl State Medical Academy)
 
  Chlamydia trachomatis & Neisseria gonorrhoeae ДНК:ПрИд:ТчкВрм:XXX:Ном:Проба.усил.мишChlamydia trachomatis & Neisseria gonorrhoeae ДНК:ПрИд:ТчкВрм:XXX:Ном:Проба.усил.миш
  Spanish (ARGENTINA)  (From: Conceptum Medical Terminology Center)
 
  [anticuerpo anti - ] Neisseria gonorrhoeae [Ac]:presencia o identidad:punto en el tiempo:XXX:Nominal:sonda.amplificación.blanco[anticuerpo anti - ] Neisseria gonorrhoeae [Ac]:presencia o identidad:punto en el tiempo:XXX:Nominal:sonda.amplificación.blanco
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Chlamydia trachomatis & Neisseria gonorrhoeae ADN:Presencia o identidad:Punto temporal:XXX:Nom:Sonda con amplificación dirigidaChlamydia trachomatis & Neisseria gonorrhoeae ADN:Presencia o identidad:Punto temporal:XXX:Nom:Sonda con amplificación dirigida

RELATED NAMES
  3 Self-Sustaining Sequence Replication GC Nucleic acid sequence based analysis
  3SR SR Gono Other
  Amplif Gonorrhea PCR
  Amplification Identity or presence Point in time
  Amplified LAT Polymerase chain reaction
  C trac LCR Probe amp
  C trach LGV Probe with ampification
  C trach+GC Ligase chain reaction Probe with target amplification
  C tracho Ligation-activated transcription QBR
  C trachomatis Lymphogranuloma venereum Random
  Chlam Microbiology SDA
  Chlam trac Misc Strand Displacement Amplification
  Chlamid Miscellaneous TMA
  CT N gonorrhoea To be specified in another part of the message
  CT + NG DNA N gonorrhoeae Trachoma
  CT/GC NAA+probe Transcription mediated amplification
  Deoxyribonucleic acid NAAT Unspecified
  DNA NUCLEIC ACID PROBE NASBA  
  DNA probe Nominal  

CHANGE HISTORY
  Change Type: MIN

INTERNAL FIELDS
  Detail Page Created On: 6/26/2019 6:11:50 PM
  Attachment Units Required: N
  Long Common Name: Chlamydia trachomatis and Neisseria gonorrhoeae DNA [Identifier] in Unspecified specimen by NAA with probe detection
  Shortname: C trach+GC DNA XXX NAA+probe
  Fully Specified Name: Chlamydia trachomatis & Neisseria gonorrhoeae DNA: Prid: Pt: XXX: Nom: Probe.amp.tar
     
  Component Word Count: 5
  ID: 29469
  Status (Raw): ACTIVE