32109-1  Phenytoin Free [Moles/​volume] in Serum or PlasmaPhenytoin Free [Moles/​volume] in Serum or PlasmaPhenytoin.free: SCnc: Pt: Ser/​Plas: Qn:  

NAME
  Fully Specified Name: 
Component   Property   Time   System   Scale   Method
Phenytoin.free  SCnc  Pt  Ser/Plas  Qn 
  Long Common Name:  Phenytoin Free [Moles/volume] in Serum or Plasma
  Short Name:  Phenytoin Free SerPl-sCnc
  Display Name:  Phenytoin Free [Moles/Vol]

PART DEFINITION/DESCRIPTION(S)
  Part: Phenytoin.free
  Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug.
 
 
  Part: free DRUG/TOX
  The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug [PMID: 6636249] . For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
 
 

BASIC ATTRIBUTES
  Class/Type: DRUG/TOX/Lab
  Common SI Lab Results Rank: #1581
  First Released in Version: 2.07
  Last Updated in Version: 2.34
  Mass or Substance Property: S
  Order vs. Obs.: Observation
  Status: Active

SUBMITTER'S INFORMATION
  Submitted Units: umol/L

MEMBER OF THESE PANELS     
  This section provides information about panels that contain this LOINC code.
  LOINC   Long Common Name  
  54037-7 HEDIS 2009 panel
  57820-3 HEDIS 2010 panel
  60442-1 HEDIS 2011 panel
  67767-4 HEDIS 2012 panel
  72199-3 HEDIS 2013 panel
  74234-6 HEDIS 2014 Value Sets
  

MEMBER OF THESE EQUIVALENCE GROUPS
  LG47569-5  Phenytoin.free|Pt|Ser/Plas

PARTS

Part Type    Part No.  Part Name   
Component   LP14731-1  Phenytoin.free   [Phenytoin Free] 
Property   LP6860-3  SCnc   [Substance Concentration] 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP7576-4  Ser/Plas   [Serum or Plasma] 
Scale   LP7753-9  Qn 
Fragments for synonyms   LP20769-3  Free 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  苯妥英.游离型:物质的量浓度:时间点:血清/​血浆:定量型:苯妥英.游离型:物质的量浓度:时间点:血清/​血浆:定量型:
  Dutch (NETHERLANDS)  (From: Regenstrief-generated full translation based on part translation provided by NVKC, Dutch Society for Clinical Chemistry and Laboratory Medicine, The Netherlands)
 
  fenytoïne.vrij:mol/​volume:moment:serum of plasma:kwantitatief:fenytoïne.vrij:mol/​volume:moment:serum of plasma:kwantitatief:
  Estonian (ESTONIA)  (From: Regenstrief-generated full translation based on part translation provided by Estonian E-Health Foundation)
 
  Fenütoiin.vaba:SCnc:Pt:S/​P:Qn:Fenütoiin.vaba:SCnc:Pt:S/​P:Qn:
  French (BELGIUM)  (From: Regenstrief-generated full translation based on part translation provided by Jean M. Prevost, MD, Biopathology)
 
  Phénytoïne.libre:Concentration de substance:Temps ponctuel:Sérum/​Plasma:Quantitatif:Phénytoïne.libre:Concentration de substance:Temps ponctuel:Sérum/​Plasma:Quantitatif:
  French (CANADA)  (From: Regenstrief-generated full translation based on part translation provided by Canada Health Infoway Inc.)
 
  Phénytoïne.libre:Concentration de substance:Temps ponctuel:Sérum/​Plasma:Quantitatif:Phénytoïne.libre:Concentration de substance:Temps ponctuel:Sérum/​Plasma:Quantitatif:
  French (FRANCE)  (From: ASIP Santé (Agence des systèmes d'information partagés de santé))
 
  Phenytoin.free:SCnc:Pt:Ser/​Plas:Qn:Phenytoin.free:SCnc:Pt:Ser/​Plas:Qn:Diphénylhydantoïne libre [Moles/​Volume] Sérum/​Plasma ; Numérique
  French (SWITZERLAND)  (From: CUMUL, Switzerland)
 
  S--phénytoïne libre
  German (GERMANY)  (From: Institute for Medical Documentation and Information (DIMDI))
 
  Phenytoin.frei:SKnz:Pkt:Ser/​Plas:Qn:Phenytoin.frei:SKnz:Pkt:Ser/​Plas:Qn:
  German (SWITZERLAND)  (From: CUMUL, Switzerland)
 
  S--Phenytoin, freie
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Fenitoina.libera:SCnc:Pt:Siero/​Plasma:Qn:Fenitoina.libera:SCnc:Pt:Siero/​Plasma:Qn:
  Italian (SWITZERLAND)  (From: CUMUL, Switzerland)
 
  S--fenitoina libera
  Korean (KOREA, REPUBLIC OF)  (From: Korean Ministry for Health, Welfare, and Family Affairs)
 
  유리페니토인:물질농도:검사시점:혈청/​혈장:정량:유리페니토인:물질농도:검사시점:혈청/​혈장:정량:
  Portuguese (BRAZIL)  (From: HL7 Brazil Institute)
 
  Fenitoína.livre:SCnc:Pt:Sor/​Plas:Qn:Fenitoína.livre:SCnc:Pt:Sor/​Plas:Qn:
  Russian (RUSSIAN FEDERATION)  (From: Regenstrief-generated full translation based on part translation provided by Yaroslavl State Medical Academy)
 
  Фенитоин.свободный:МолКонц:ТчкВрм:Сыв/​Плаз:Колич:Фенитоин.свободный:МолКонц:ТчкВрм:Сыв/​Плаз:Колич:
  Spanish (ARGENTINA)  (From: Conceptum Medical Terminology Center)
 
  fenitoína.libre:concentración de sustancia:punto en el tiempo:suero/​plasma:cuantitativo:fenitoína.libre:concentración de sustancia:punto en el tiempo:suero/​plasma:cuantitativo:
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Fenitoína libre:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:Fenitoína libre:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
  Spanish (SWITZERLAND)  (From: CUMUL, Switzerland)
 
  S--fenitoina libre
  Turkish (TURKEY)  (From: Regenstrief-generated full translation based on part translation provided by LOINC Turkish Translation Group and the Turkish Ministry of Health)
 
  Fenitoin.serb:SubKons:Zmlı:Ser/​Plaz:Kant:Fenitoin.serb:SubKons:Zmlı:Ser/​Plaz:Kant:

RELATED NAMES
  DI-HYDAN Non-protein bound Random
  Dilantin Phenhydan SerP
  Dilj Phenytoin Free SerPl
  Diphenylhydantoin PHYT SerPlas
  DPH Pl Serum
  DRUG/TOXICOLOGY Plasma Serum or plasma
  Drugs Plsm Sinergina
  Epanutin Point in time SR
  Fenantoin QNT Substance concentration
  FR Quan Zentropil
  Lehydan Quant  
  Level Quantitative  

EXAMPLE UNITS
  Unit  Source Type
  umol/L  EXAMPLE UCUM UNITS 
  umol/L  ORIGINAL SUBMISSION 
  umol/L  eCHN 

UNITS (INTERNAL DETAILS)
  Source Type:  EXAMPLE UCUM UNITS 
  Unit:  umol/L 
  Source Type:  ORIGINAL SUBMISSION 
  Unit:  umol/L 
  Source Type:  eCHN 
  Unit:  umol/L 

CHANGE HISTORY
  Change Type: MIN

INTERNAL FIELDS
  Detail Page Created On: 6/26/2019 6:32:18 PM
  Attachment Units Required: N
  Long Common Name: Phenytoin Free [Moles/volume] in Serum or Plasma
  Shortname: Phenytoin Free SerPl-sCnc
  Fully Specified Name: Phenytoin.free: SCnc: Pt: Ser/Plas: Qn:
     
  Component Word Count: 2
  ID: 24188
  Status (Raw): ACTIVE