Version 2.77

Description

Probe with signal amplification is a lab method that uses a hybridization probe, which is a typically a short nucleic acid segment that binds to a complementary nucleic acid sequence that is specific to the target of interest, followed by a signal enhancement step, in which the signal that is generated when the probe binds to the target sequence is multiplied so that it is "brighter" and easier to detect. Signal amplification can be done using different techniques, including the branched-chain DNA (bDNA) method. In theory, signal amplification is more sensitive than a probe by itself because it generates a brighter signal per each copy of the target sequence that is present. In LOINC, the probe.amp.sig method is assigned to codes for assays that do not include a nucleic acid amplification step. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Probe with signal amplification
Part Type
Method (Describes the method by which the test was performed)
Created On
2000-05-03
Construct for LOINC Short Name
Probe+sig amp

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP6463-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 探针法.基因扩增.信号
Synonyms: 借助信号扩增的探针方法;借助信号扩增的探针法;探针法.扩增.信号;支链 DNA;支链 DNA（Branched Chain DNA，bDNA）;杂交保护分析;杂交保护分析（Hybidization Protection Assay，HPA）;杂交保护测定;杂种捕获;杂种捕获（Hybrid Capture）;杂种捕获核酸杂交（Hybrid Capture nucleic acid hybridization）
fr-CA French (Canada) Sonde avec amplification du signal
es-ES Spanish (Spain) Sonda con amplificación de señal
it-IT Italian (Italy) Sonda.amp.sig
Synonyms: Sonda con amplificazione del segnale
el-GR Greek (Greece) Ανιχνευτής με ενίσχυση σήματος
tr-TR Turkish (Turkey) Prob.amf.siny
ru-RU Russian (Russian Federation) Проба.усил.сигн
Synonyms: Проба с сигнала усилением
nl-NL Dutch (Netherlands) probe.amp.sig
fr-BE French (Belgium) Sonde avec amplification du signal