LP28774-5
Pregnancy associated plasma protein A
Active
Descriptions
Pregnancy associated plasma protein A (PAPPA), also known as pappalysin 1, is used in screening for Down syndrome and other fetal disorders. Source: Regenstrief Institute
Pregnancy-associated plasma protein A (PAPP-A), an important pregnancy protein is a major biochemical marker of Down syndrome in the first trimester of pregnancy. The gene of PAPP-A is assigned to human chromosome 9q 33.1. PAPP-A belongs to the metzincin superfamily of metalloproteinases. Maternal serum levels of PAPP-A in the first trimester are significantly lower if the fetus is affected by Down syndrome. Low first trimester maternal serum levels are found not only in trisomy 21 but also in non-Down syndrome fetal aneuploidies. PAPP-A may also be an indicator of stable and unstable angina pectoris. PMID: 12448565 Source: Regenstrief LOINC, PMID: 12448565
Basic Part Properties
- Part Display Name
- Pregnancy associated plasma protein A
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2002-04-29
- Construct for LOINC Short Name
- PAPP-A
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 妊娠相关血浆蛋白 A Synonyms: PAPP-A; |
| fr-CA | French (Canada) | Protéine A plasmatique associée à la grossesse |
| et-EE | Estonian (Estonia) | Rasedusega seotud plasmaproteiin A |
| es-ES | Spanish (Spain) | Proteína A del plasma asociada al embarazo |
| it-IT | Italian (Italy) | Proteina A plasmatica associata alla gravidanza |
| tr-TR | Turkish (Turkey) | Gebelik ilişkili plazma protein A |
| ru-RU | Russian (Russian Federation) | Беременность-ассоциированный плазматический протеин А Synonyms: Беременность-ассоциированный плазматический белок А |
| nl-NL | Dutch (Netherlands) | PAPP-A Synonyms: pregnancy associated plasma protein A |
| fr-BE | French (Belgium) | Protéine A plasmatique associée ? la grossesse Synonyms: PAPPA |
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