Version 2.77

Description

Cell-free DNA (cfDNA) is DNA that circulates in the plasma, and in pregnant women, cfDNA is both maternal and fetal in origin. Fetal cfDNA can be detected in maternal plasma as early as 7 weeks' gestation and the proportion of fetal cfDNA increases during the pregnancy. Fetal cfDNA is continuously added to maternal circulation and is cleared within hours. Certain noninvasive prenatal screening tests analyze maternal cfDNA to determine the fetal risk for a variety of genetic disorders. The proportion of cfDNA, calculated as fetal cfDNA/total cfDNA and also known as fetal fraction, is one of the reported measures, and in general, samples with a higher fetal fraction yield more sensitive results than those with lower fetal fraction. PMID: 24466384 Source: Regenstrief LOINC, PMID: 24466384

Basic Part Properties

Part Display Name
Plasma cell-free DNA
Part Type
System (Describes the name of the system (sample) type)
Created On
2014-08-18
Construct for LOINC Short Name
Plas.cfDNA

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP185795-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 血浆.cfDNA
Synonyms: 血浆循环 cfDNA;血浆循环 DNA;循环游离核酸;血浆游离 DNA;血浆无细胞 DNA;Free circulating/Cell-free DNA;Free circulating DNA
es-ES Spanish (Spain) ADN en plasma libre de células
it-IT Italian (Italy) Plasma.DNA libero circolante
Synonyms: DNA libero circolante nel plasma
tr-TR Turkish (Turkey) Plaz.cfDNA
Synonyms: Plazma hücresiz DNA
nl-NL Dutch (Netherlands) plasma.celvrij DNA
Synonyms: circulerend DNA
pl-PL Polish (Poland) pozakomórkowy DNA w osoczu