Version 2.77

Description

Estrogen receptor refers to a group of receptors which are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.

The main function of the estrogen receptor is as a DNA binding transcription factor which regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding.

Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive", and can be demonstrated in such tissues using immunohistochemistry. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Estrogen receptor

Basic Part Properties

Part Display Name
Estrogen receptor
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
ER

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP18567-5

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 雌激素受体
Synonyms: ER;ERA;雌激素受体（Estrogen Receptor，ER）
fr-CA French (Canada) Récepteur de l'œstrogène
et-EE Estonian (Estonia) Östrogeeni retseptor
es-ES Spanish (Spain) Receptor de estrógeno
it-IT Italian (Italy) Estrogeno, recettore
Synonyms: Recettore degli estrogeni
tr-TR Turkish (Turkey) Östrojen reseptörü
ru-RU Russian (Russian Federation) Эстроген рецептор
Synonyms: Рецептор к эстрогену
nl-NL Dutch (Netherlands) oestrogeenreceptor
fr-BE French (Belgium) Récepteur d'œstrogène
Synonyms: Récepteur d''oestrogènes