Version 2.77

Descriptions

A species of gram-negative bacteria in the genus Anaplasma, family Anaplasmataceae, formerly called Ehrlichia phagocytophila or Ehrlichia equi. This organism is tick-borne (Ixodes) and causes disease in horses and sheep. In humans, it causes human granulocytic ehrlichiosis. Source: National Library of Medicine, MeSH 2006

Human Granulocytic Ehrlichiosis (HGE) is an illness caused by a rickettsial bacteria transmitted by deer and dog ticks to humans. With HGE, also known as Human Granulocytic Anaplasmosis (HGA), neutrophils become infected by Anaplasma phagocytophilum and clusters of small bacteria may be seen within the neutrophils on blood smears during the terminal phases of the infection. Patients may exhibit fever, headache, malaise, myalgia, no skin rash, decreased WBC and platelet count and mild liver injury may also occur be present. Information from Emerg. Infect Dis.2005;11(12);2005 Centers for Disease Control and Prevention. Source: Regenstrief Institute

Anaplasma phagocytophilum is a rickettsial bacterium (formerly known as Ehrlichia phagocytophilum or Ehrlichia equi) that infects white blood cells and causes human granulocytic ehrlichiosis (HGE), also called human granulocytic anaplasmosis (HGA). A. phagocytophilum is a pathogen transmitted to humans by the bite of a tick (i.e., American dog tick, deer tick, and Lone Star tick), and may pose a risk of being transmitted by blood transfusion. The first symptoms of HGE/HGA normally begin one to two weeks after a tick bite, but a negative test for antibodies during the first seven to 10 days of illness is not always accurate. Both immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies usually rise near the end of the first week of illness. IgM antibodies are less specific than IgG antibodies and more likely to result in a false positive, so a concurrent IgG titer should also be run. Repeat testing several weeks after the original test, including comparison of antibody titers between the two time periods, is recommended. For IgG, the first sample typically shows a low or negative result, and the second typically shows a significant (four-fold) increase in IgG antibody levels. [https://www.cdc.gov/anaplasmosis/symptoms/index.html] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Anaplasma phagocytophilum
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
A phagocytoph

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 嗜吞噬球无形体
Synonyms: 人粒细胞埃立克体;人粒细胞埃立克体病;吞噬细胞埃立克体;马埃立克体
fr-CA French (Canada) Anaplasma phagocytophilum
et-EE Estonian (Estonia) Anaplasma phagocytophilum
es-ES Spanish (Spain) Anaplasma phagocytophilum
it-IT Italian (Italy) Anaplasma phagocytophilum
tr-TR Turkish (Turkey) Anaplazma phagocytophilum
ru-RU Russian (Russian Federation) Anaplasma phagocytophilum
nl-NL Dutch (Netherlands) Anaplasma phagocytophilum
fr-BE French (Belgium) Anaplasma phagocytophilum