Version 2.77

Descriptions

Hemoglobin F is used to screen for fetal-to-maternal hemorrrhage. The presence of fetal red cells in the maternal circulation may be identified by use of the acid elution principle first described by Kleihauer, Brown, and Betke, or by several modifications. Very small volumes of red cells commonly escape from the fetal intravascular compartment across the placental barrier into the maternal intervillous space. Source: Regenstrief Institute

Fetal hemoglobin, or foetal haemoglobin, (also hemoglobin F or HbF) is the main oxygen transport protein in the fetus during the last seven months of development in the uterus and in the newborn until roughly 6 months old. Functionally, fetal hemoglobin differs most from adult hemoglobin in that it is able to bind oxygen with greater affinity than the adult form, giving the developing fetus better access to oxygen from the mother's bloodstream.

In newborns, fetal hemoglobin is nearly completely replaced by adult hemoglobin by approximately 6 months postnatally. In adults, fetal hemoglobin production can be reactivated pharmacologically, which is useful in the treatment of diseases such as sickle-cell disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Reference Information

Type Source Reference
Article Regenstrief Institute Fibach E, Flow cytometric analysis of fetal hemoglobin in RBC and their precursors. Fetal Hemoglobin

Basic Part Properties

Part Display Name
Hemoglobin F
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Hgb F

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16428-2

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 血红蛋白 F
Synonyms: HbF;Hgb F;胎儿血红蛋白
fr-CA French (Canada) Hémoglobine F
et-EE Estonian (Estonia) Hemoglobiin F
es-ES Spanish (Spain) Hemoglobina fetal
it-IT Italian (Italy) Emoglobina F
tr-TR Turkish (Turkey) Hemoglobin F
ru-RU Russian (Russian Federation) Гемоглобин F
nl-NL Dutch (Netherlands) hemoglobine F
fr-BE French (Belgium) Hémoglobine F
Synonyms: HbF
pl-PL Polish (Poland) Hemoglobina F