Version 2.77

Description

Phenobarbital is an antiepileptic drug first introduced for clinical use in 1912. It is still used to treat most seizures except for absence seizure types. The CYP2C19 enzyme metabolizes phenobarbital to p-hydroxyphenobarbital which is then excreted as glucuronide. Phenobarbital induces secretion of liver enzymes which can impact the efficacy of drugs administered at the same time. The most common side effect of phenobarbital in adults with blood levels greater than 40 mg/L is sedation. Phenobarbital is an active metabolite of primidone and so must also be monitored in patients on primidone.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns) Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
PHENobarbital
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Phenobarb

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14729-5
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 苯巴比妥
Synonyms: C12H12N2O3;苯巴比妥米那;鲁米那;苯基巴比妥;本巴比妥
fr-CA French (Canada) Phénobarbital
et-EE Estonian (Estonia) Fenobarbitaal
es-ES Spanish (Spain) Fenobarbital
it-IT Italian (Italy) Fenobarbital
el-GR Greek (Greece) Φαινοβαρβιτάλη
tr-TR Turkish (Turkey) Fenobarbital
ru-RU Russian (Russian Federation) Фенобарбитал
nl-NL Dutch (Netherlands) fenobarbital
fr-BE French (Belgium) Phénobarbital