Version 2.77

Description

Myelin basic protein (MBP) is important in the process of myelination of nerves in the central nervous system (CNS). MBP was initially sequenced in 1979 after isolation from myelin membranes. Since that time, knockout mice deficient in MBP have been developed which showed decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death. The gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic system. The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation and citrullination. Interest in MBP has centered on its role in demyelinating diseases, particularly multiple sclerosis (MS). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Myelin basic protein (Wikipedia)

Basic Part Properties

Part Display Name
Myelin basic protein
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
MBP

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14685-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 髓磷脂碱性蛋白
Synonyms: MBP;骨磷脂碱性蛋白;髓磷脂碱性蛋白(Myelin Basic Protein,MBP);髓鞘质碱性蛋白
fr-CA French (Canada) Protéine basique de la myeline
es-ES Spanish (Spain) Proteína básica de la mielina
it-IT Italian (Italy) Mielina, proteina basica
Synonyms: Proteina basica della mielina
tr-TR Turkish (Turkey) Miyelin bazik protein
ru-RU Russian (Russian Federation) Миелина основной протеин
Synonyms: Миелина основной белок
nl-NL Dutch (Netherlands) myeline basic proteïn
fr-BE French (Belgium) Protéine basique de la myéline