Version 2.77

Description

Alpha-1-fetoprotein (AFP) is a key variable in prenatal screening for the detection of trisomy 18, 21 and neural tube defect. It is also the primary tumor marker for nonseminomatous testicular cancers. Post-operative AFP levels that remain above normal imply residual tumor, and/or tumor recurrence. AFP can be high in up to 70% of patients with primary hepatocellular carcinoma. Elevated AFP levels have occasionally been found in association with gastrointestinal tract cancers.
Serum AFP is also elevated in ataxia telangiectasia, hereditary tyrosinemia, teratocarcinoma, and non-cancerous hepatic conditions, such as acute viral hepatitis, chronic active hepatitis and cirrhosis. Elevation of serum AFP in non-cancerous hepatic diseases is usually transient. Source: Regenstrief Institute

Basic Part Properties

Part Display Name
Alpha-1-Fetoprotein
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
AFP

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14331-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) Alpha-1-胎儿球蛋白
Synonyms: A1 胎儿球蛋白;A1 胎蛋白;A-1-胎儿球蛋白;A1-胎儿球蛋白;A-1-胎蛋白;A1-胎蛋白;AFP;Alpha 1 胎儿球蛋白;Alpha 1 胎蛋白;Alpha1 胎儿球蛋白;Alpha1 胎蛋白;Alpha1-胎儿球蛋白;Alpha-1-胎蛋白;Alpha1-胎蛋白;α1 胎儿球蛋白;α1 胎蛋白;α1-胎儿球蛋白;α1-胎蛋白;甲胎蛋白;胎甲球
fr-CA French (Canada) Alpha-1-foetoprotéine
et-EE Estonian (Estonia) Alfafetoproteiin
es-ES Spanish (Spain) Alfa-1-Fetoproteina
it-IT Italian (Italy) Alfa-1-Fetoproteina
el-GR Greek (Greece) α1-εμβρυϊκή πρωτεΐνη
tr-TR Turkish (Turkey) Alfa-1-Fetoprotein
ru-RU Russian (Russian Federation) Альфа-1-фетопротеин
nl-NL Dutch (Netherlands) alfa-1-foetoproteïne
fr-BE French (Belgium) Alpha-1-foetoprotéine
Synonyms: AFP