89504-5

Ribosomal Ab [Presence] in Serum by Line blot

Active

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP18386-0   Ribosomal
A ribosome is an organelle in cells that assembles proteins. Ribosomes are composed of ribosomal RNA and ribosomal proteins (known as a Ribonucleoprotein or RNP). It translates Messenger RNA (mRNA) into a polypeptide chain (e.g., a protein). It can be thought of as a factory that builds a protein from a set of genetic instructions. Ribosomes can float freely in the cytoplasm (the internal fluid of the cell) or bind to the endoplasmic reticulum, or to the nuclear envelope. Since ribosomes are ribozymes, it is thought that they might be remnants of the RNA world. Ribosomes were first observed in the mid-1950s by cell biologist George Palade in the electron microscope as dense particles or granules for which he would win the Nobel Prize. The term ribosome was proposed by scientist Richard B. Roberts in 1958: During the course of the symposium a semantic difficulty became apparent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ribosomal (Wikipedia)

LP18386-0   Ribosomal
There are several ribosomal antigens. P (phospho) protein (P0, P1 & P2) is the most common. Other ribosomal antigens are L12 protein, L5/5s, S10, Ja, L7 and rRNA (ribosomal ribonucleoprotein) Source: Regenstrief Institute

Fully-Specified Name

Component

Ribosomal Ab

Property

PrThr

Time

Pt

System

Ser

Scale

Ord

Method

Line blot

Additional Names

Short Name

Ribosomal Ab Ser Ql Line blot

Display Name

Ribosomal Ab Line blot Ql (S)

Consumer Name Alpha Get Info

Ribosomal antibody, Blood

Example Answer List: LL744-4

Basic Attributes

Class

SERO

Type

Laboratory

First Released

Version 2.64

Last Updated

Version 2.64

Order vs. Observation

Both

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Autoantibodies
• Autoantibody
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Serology
• Serum
• SR

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.

CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89504-5

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.