88182-1

Wuchereria bancrofti+Brugia malayi IgG1 Ab [Presence] in Serum by Immunoassay

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Part Description

LP35808-2   Wuchereria bancrofti+Brugia malayi
Wuchereria bancrofti, Brugia malayi and Brugia timori are the three species of filaria that cause lymphatic filariasis in humans living in the tropics and sub-tropics. Infection is spread from person to person by mosquito bites. The adult worms live and reproduce in the human lymphatic system, creating millions of microscopic worms called microfilariae. When a person who is infected is bitten by a mosquito, the mosquito becomes infected, and the microfilariae mature inside the mosquito. When the mosquito bites another person, the larval worms are passed from the mosquito to the human and travel to the lymphatic system, where they grow into adult worms. Most people with lymphatic filariasis are asymptomatic, and a few develop lymphedema, primarily in the legs, but also in the arms, breasts, and genitals. People with lymphedema are more susceptible to bacterial infections of the skin and lymphatic system, which can lead to hardening and thickening of the skin, also known as elephantiasis.
Filarial infection can also cause tropical pulmonary eosinophilia syndrome. Lymphatic filariasis primarily develops in people who have gotten mosquito bites in an endemic area over an extended period of time. [https://www.cdc.gov/parasites/lymphaticfilariasis/] Studies have shown that different IgG isotypes may characterize different stages of infection. IgG1, IgG2 and IgG3 are most common in asymptomatic patients, while IgG4 is a marker of active infection. PMID: 28118850 In addition, larval antigens may have a stronger IgG1 response, followed by IgG2 and IgG3, while IgG4 is the most common isotype found in response to adult filaria. PMID: 9491413 Source: Regenstrief LOINC

Fully-Specified Name

Component

Wuchereria bancrofti+Brugia malayi Ab.IgG1

Property

PrThr

Time

Pt

System

Ser

Scale

Ord

Method

IA

Additional Names

Short Name

W bancr+B malayi IgG1 Ser Ql IA

Display Name

W. bancrofti+Brugia malayi IgG1 Ab IA Ql (S)

Consumer Name Alpha Get Info

Wuchereria bancrofti+Brugia malayi IgG1 antibody, Blood

Example Answer List: LL744-4

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.63

Last Updated

Version 2.63

Order vs. Observation

Both

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Autoantibodies
• Autoantibody
• B malayi
• Bancroftian filariasis
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• Filariasis
• Human lymphatic filariasis
• IAA
• ID
• IgG 1
• IgG subgroup 1
• Infectious Disease
• InfectiousDisease
• MEIA
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Serum
• SR
• SUDS
• W bancr
• W bancr+B malayi
• W bancrofti
• Wucheria bancrofti

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.