80588-7

Influenza virus A M gene [Presence] in Nasopharynx by NAA with probe detection

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Term Description

Detection of targeted nucleic acid sequences in the Influenza A matrix protein (M) gene RNA by PCR-based methods. This term was created for, but not limited in use to, the Verigene® Respiratory Pathogens Flex Nucleic Acid Test (RP Flex), a multiplexed, qualitative test for the detection and identification of multiple viral and bacterial genetic virulence markers from nasopharyngeal swab specimens.
Source: Regenstrief LOINC

Part Descriptions

LP206581-3 Influenza virus A M gene
The matrix protein gene of influenza virus A encodes two proteins: a matrix protein (M1) and an ion channel protein (M2). M1 plays a critical role in virus structure and replication by building connections between the viral lipid membrane and ribonucleoprotein (RNP) core. M1 also binds to RNPs in the nucleus, inhibiting viral transcription. The ion channel (M2) protein spans the lipid bilayer. Source: Regenstrief LOINC

LP206581-3 Influenza virus A M gene
The influenza virus A (FLUVA) genome is composed of eight gene segments (PB2, PB1, PA, HA, NP, NA, M, NS1) that code for 11 proteins. Two of the genes, hemagglutinin (HA) and neuraminidase (NA), determine the structure of the two primary surface proteins of influenza viruses. The HA and NA gene sequences are used to determine the Influenza virus subtype. Currently there are 16 subtypes of HA and 9 subtypes of NA known, but only H 1, 2 and 3, and N 1 and 2 are commonly found in humans. PMID: 17458769 The M gene segment, which encodes two matrix proteins (M1 and M2), may also be used as a target in PCR-based assays for detection of FLUVA in various specimens. Source: Regenstrief LOINC

LP206581-3 Influenza virus A M gene
The influenza A virus (FLUAV) is a common respiratory virus that infects humans as well as birds, horses, seals, dogs, and pigs. There are eight gene segments that make up the negative single-stranded RNA of the FLUAV. The gene segments are known as PB1, PB2, PA, NP, HA, NA, M, and NS. The M gene is the seventh segment and encodes the M1 (matrix protein) and M2 (membrane) proteins. [https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-6-67] The M1 protein is located beneath the lipid membrane and functions to give support and strength to the viral envelope. The M2 transmembrane protein is an ion channel that assists to uncover the virus once it is inside the host cell. M1 and NP proteins together determine whether the influenza virus is type A, B, or C. M1 brings viral constituents together to the assembly location, playing important roles in the creation of viral particles and in the budding process.[http://www.clinlabnavigator.com/influenza-virus-subtypes.html] Source: Regenstrief LOINC

Fully-Specified Name

Component: Influenza virus A M gene
Property: PrThr
Time: Pt
System: Nph
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: FLUAV M gene Nph Ql NAA+probe
Display Name: FLUAV M gene NAA+probe Ql (Nph)
Consumer Name Alpha Get Info: Influenza A M gene, Nasopharynx

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.73
Order vs. Observation: Both
Common Test Rank Get Info: 6590

Member of these Panels

LOINC	Long Common Name
78922-2	Respiratory pathogens DNA and RNA panel - Nasopharynx by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG32757-3	Influenza virus

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Influenza-Virus A M-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Nasopharynx:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Genes A+B Metapneumovirus humano:PrThr:Punto temporal:Nasofaringe:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	Gen A M del virus de la influenza:Presencia o umbral:Punto temporal:Nasofaringe:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Influenza virus A gène M:Présence/Seuil:Ponctuel:Nasopharynx:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Virus Influenza A gene M:PrThr:Pt:Nph:Ord:Sonda.amp.tar Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Rinofaringe Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A
nl-NL	Dutch (Netherlands)	Influenzavirus A M-gen:aanwezigheid:moment:neusholte:ordinaal:probe-detectie Synonyms: Influenza virus A M gen probe.amp.tar
zh-CN	Chinese (China)	流感病毒 A 型 M 基因:存在情况或阈值:时间点:鼻咽:序数型:探针法.基因扩增.靶向 Synonyms: A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 FLUV;Influ;列性感冒病毒;流行性感冒病毒 M 型传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间流行性感冒病毒 A 型 M 基因;甲型流感病毒 M 基因经过扩增的脱氧核糖核酸探针遗传基因;遗传因子;吉恩;生物基因鼻咽标本;鼻咽部;鼻咽部标本

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