80353-6

Herpes simplex virus 1 genome DNA polymerase region B+thymidine kinase region C [Presence] in Anogenital specimen by NAA with probe detection

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Term Description

This assay detects herpes simplex virus (HSV) 1 using two different probes, one for genome DNA polymerase region B and one for thymidine kinase region C. If either of the probes produces a sufficient signal the result is considered positive. This term was created for, but is not limited in use to, the Roche cobas® HSV 1 and 2 Test, which is intended for use as an aid in diagnosis of anogenital HSV-1 and HSV-2 infections in symptomatic patients. The cobas HSV 1 and 2 Test is not FDA cleared for use with cerebrospinal fluid (CSF) and is not intended to be used for prenatal screening or for individuals under the age of 18 years.
Source: Regenstrief LOINC

Part Description

LP200490-3 Herpes simplex virus 1 genome DNA polymerase region B+thymidine kinase region C
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of the herpes virus family, Herpesviridae, which cause infections in humans. Eight members of herpes virus family infect humans and cause a variety of illnesses including cold sores, chickenpox or varicella, shingles or herpes zoster (VZV), cytomegalovirus (CMV). Some herpes viruses have been implicated in certain cancers and in the inflammation of the brain (encephalitis). All viruses in the herpes family produce life-long infections.
They are also called Human Herpes Virus 1 and 2 (HHV-1 and HHV-2) and are neurotropic and neuroinvasive viruses; they enter and hide in the human nervous system, accounting for their durability in the human body. HSV-1 is commonly associated with herpes outbreaks of the face known as cold sores or fever blisters, whereas HSV-2 is more often associated with genital herpes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Herpes simplex virus 1

Fully-Specified Name

Component: Herpes simplex virus 1 genome DNA polymerase region B+thymidine kinase region C
Property: PrThr
Time: Pt
System: Anogenital
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: HSV 1 DNA pol regB+TK regC Anogn Ql NAA+pr
Display Name: HSV 1 genome DNA polymerase region B+thymidine kinase region C NAA+probe Ql (Anogenital)
Consumer Name Alpha Get Info: Herpes simplex virus (HSV) 1 Genome DNA Polymerase Region B+thymidine Kinase Region C, Anogenital

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.63
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
80354-4	Herpes simplex virus 1 and 2 DNA panel - Anogenital specimen by Probe and target amplification method

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Genoma Herpes simplex virus 1 ADN polimerasa region B+timidina quinasa region C:PrThr:Punto temporal:Anogenital:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	Virus del herpes simplex 1 genoma ADN polimerasa región B + timidina quinasa región C:Presencia o umbral:Punto temporal:Anogenital:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Herpes simplex virus 1 ADN polymérase région B+ thymidine kinase région C:Présence/Seuil:Ponctuel:Anogénital:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Herpes simplex virus 1 genoma della regione polimerasi B del DNA+regione C della timidina chinasi:PrThr:Pt:Anogenitale:Ord:Sonda.amp.tar Synonyms: HSV HSV-1 Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	herpes-simplexvirus 1 genoom DNA polymerase gebied B + thymidine kinase gebied C:aanwezigheid:moment:anogenitaal:ordinaal:probe-detectie Synonyms: probe.amp.tar
tr-TR	Turkish (Turkey)	Herpes simplex virüs 1 genom DNA polimeraz bölgesi B+timidin kinaz bölgesi C:MevcEşik:Zmlı:Anogenital:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	单纯疱疹病毒 1 基因组 DNA 聚合酶区域 B+胸腺嘧啶核苷激酶区域 C:存在情况或阈值:时间点:肛门生殖器:序数型:探针法.基因扩增.靶向 Synonyms: Ⅰ B 型 C 型;丙;丙型 HSV;Herpes simplex virus;单疱病毒;单疱 HSV1;单纯疱疹病毒 I 型 I TK 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向区;地区;局部单纯疱疹病毒（HSV、Herpes simplex virus、单疱病毒、单疱） 1 基因组 DNA 聚合酶（多聚酶）区域（区） B+胸腺嘧啶核苷激酶（胸苷激酶、胸腺嘧啶激酶、TK）区域（区） C 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间经过扩增的肛门与生殖器;肛门生殖器（肛门与生殖器）标本（样品、体系、试样）胸腺嘧啶核苷;胸腺定;胸苷;脱氧胸苷脱氧核糖核酸探针

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