Version 2.77

Term Description

Trough levels of carbamazepine free and total along with levels for 10,11-epoxide are measured for therapeutic anticonvulsant monitoring.
Source: Regenstrief LOINC

Part Description

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
78434-8 carBAMazepine free and total trough and 10,11-Epoxide panel - Serum or Plasma
Indent74974-7 carBAMazepine free [Mass/volume] in Serum or Plasma --trough mg/L
Indent74973-9 carBAMazepine [Mass/volume] in Serum or Plasma --trough mg/L
Indent9415-1 Carbamazepine 10,11-Epoxide [Mass/volume] in Serum or Plasma ug/mL

Fully-Specified Name

Component
carBAMazepine free & total trough & 10,11-Epoxide panel
Property
-
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Carbmzpn Trgh + Metab Pnl SerPl
Display Name
carBAMazepine free and total trough and 10,11-Epoxide panel
Consumer Name Alpha Get Info
Free and Total Trough and 10,11-Epoxide carBAMazepine panel, Blood

Basic Attributes

Class
PANEL.DRUG/TOX
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de carbamazepina libre y total valle y 10,11-Epoxido:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) libre de carBAMazepina y canal total y panel de 10,11-epóxido:-:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR French (France) Carbamazépine libre et totale taux résiduel et époxycarbamazépine panel:-:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Carbamazepina libera & valore minimo totale & 10,11-Epossido, panel:-:Pt:Siero/Plasma:Qn:
Synonyms: Carbamazepina libera Livelli farmacologici e tossicologia Panel Carbamazepina libera & valore minimo totale Plasma Punto nel tempo (episodio) Set di prescrizione per livelli farmacologici e to Siero Siero o Plasma
tr-TR Turkish (Turkey) Karbamazepin serbest ve total en düşük ve 10,11-Epoksid panel:-:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 游离型与总卡马西平波谷与 10,11-环氧化物组套:-:时间点:血清/血浆:定量型:
Synonyms: C15H12N2O;叉颠宁;氨甲酰氮卓;氨甲酰氮草;立痛定;酰胺咪嗉 全体数量 全部 共计 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.药物/毒理学试验;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.药物/毒理学;医嘱组.药物与毒理学;医嘱组.药物与毒理学试验;医嘱组类.药物/毒理学;医嘱组类.药物/毒理学试验;医嘱组类.药物与毒理学;医嘱组类.药物与毒理学试验;实验室医嘱组类.药物/毒理学;实验室医嘱组类.药物/毒理学试验;实验室医嘱组类.药物与毒理学;实验室医嘱组类.药物与毒理学试验;药物与毒理学医嘱组;药物与毒理学医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 卡马西平.游离;游离卡马西平;游离型卡马西平;游离型卡马西平（叉颠宁、氨甲酰氮卓、氨甲酰氮草、立痛定、酰胺咪嗉） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 毒品 毒品类 汇总 游离 游离型与总卡马西平（叉颠宁、氨甲酰氮卓、氨甲酰氮草、立痛定、酰胺咪嗉）波谷（谷值、低谷、最小值、最低点）与 10,11-环氧化物组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 组 组合 组合医嘱 组合类 组套 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78434-8
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/78434-8