Version 2.77

Term Description

Ornithine/Citrulline is a marker for gyrate atrophy of the retina, ornithine transcarbamylase deficiency, carbamoyl-phosphate synthase deficiency, and hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, which are all conditions that some states include on their newborn screening panel.
Source: Regenstrief LOINC

Part Descriptions

LP15753-4   Ornithine
Ornithine is an amino acid that, under the action of the enzyme arginase on L-arginine, yields urea. Therefore, ornithine is a central part of the urea cycle, which eliminates excess nitrogen. Ornithine is not an amino acid coded by DNA, and in that sense, it is not involved in protein synthesis. In mammalian non-hepatic tissues, however, the urea cycle is mainly involved in arginine biosynthesis, making ornithine an important metabolic process. It is not directly a product of the the genetic code because polypeptides containing unprotected ornithines undergo spontaneous lactamization. This proved to be a problem when ornithine was originally classified among the other 20 naturally occuring amino acids. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ornithine (Wikipedia)

LP15753-4   Ornithine
An amino acid produced in the urea cycle when the enzyme arginase cleaves off urea from arginine. Source: National Library of Medicine, MeSH 2006

LP70358-4   Citrulline
Citrulline is an alpha amino acid, produced from ornithine and carbamoyl phosphate during the urea cycle. Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Citrulline (Wikipedia)

Fully-Specified Name

Component
Ornithine/Citrulline
Property
SRto
Time
Pt
System
Bld.dot
Scale
Qn
Method

Additional Names

Short Name
Ornithine/Cit DBS-sRto
Display Name
Ornithine/Citrulline (DBS) [Molar ratio]
Consumer Name Alpha Get Info
Ornithine/Citrulline, Dried blood spot

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
19291

Member of these Panels

LOINC Long Common Name
104191-2 Guanidinoacetate methyltransferase (GAMT) deficiency newborn screening panel
104188-8 Mucopolysaccharidosis type II newborn screening panel
54089-8 Newborn screening panel American Health Information Community (AHIC)

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Ornitina/Citrulina:Relacion de Sustancia:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Ornitina / Citrulina:Proporción de sustancia:Punto temporal:DBS:Cuantitativo:
fr-CA French (Canada) Ornithine/Citrulline:Ratio de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
fr-FR French (France) Ornithine/citrulline:Moles ratio:Ponctuel:Sang buvard:Numérique:
fr-BE French (Belgium) Ornithine/Citrulline:Ratio de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
it-IT Italian (Italy) Ornitina/Citrullina:Srto:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza Sangue Spot sangue secco
nl-NL Dutch (Netherlands) ornithine/citrulline:molaire verhouding:moment:gedroogde bloedspot:kwantitatief:
pt-BR Portuguese (Brazil) Ornitina/Citrulina::Pt:SgPapel:Qn:
ru-RU Russian (Russian Federation) Орнитин/Цитруллин:МольОтн:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Количественный Кровь Кровь сухая капля Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR Turkish (Turkey) Ornitin/Sitrüllin:SOrn:Zmlı:Kan.nokta:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) 鸟氨酸/瓜氨酸:物质的量比率:时间点:全血.斑点:定量型:
Synonyms: 2,5-二氨基戊酸;Orn Citr 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 血;血液

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75215-4