Version 2.77

Part Descriptions

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Fully-Specified Name

Component
carBAMazepine.free^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
carBAMazepine free Trough SerPl-mCnc
Display Name
carBAMazepine free trough [Mass/Vol]
Consumer Name Alpha Get Info
Free carBAMazepine trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.48
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
78434-8 carBAMazepine free and total trough and 10,11-Epoxide panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Carbamazepina libre^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) carBAMazepine.libre ^ a través:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Karbamasepiin.vaba^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Carbamazépine.libre^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Carbamazépine libre taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Carbamazépine.libre^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
it-IT Italian (Italy) Carbamazepina.libera^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Carbamazepina libera Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL Dutch (Netherlands) carbamazepine.vrij^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Carbamazepina.livre^basal::Pt:Soro/Plas:Qn:
ru-RU Russian (Russian Federation) Карбамазепин.свободный^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Karbamazepin.serb^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CN Chinese (China) 卡马西平.游离型^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: C15H12N2O;叉颠宁;氨甲酰氮卓;氨甲酰氮草;立痛定;酰胺咪嗉 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 卡马西平.游离;游离卡马西平;游离型卡马西平;游离型卡马西平（叉颠宁、氨甲酰氮卓、氨甲酰氮草、立痛定、酰胺咪嗉） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 游离 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

Example Units

Unit Source
mg/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74974-7