Version 2.77

Term Description

IgG antibodies to HLA Class II (HLA-DP+DQ+DR) glycoproteins are detected in patient's serum or plasma by EIA methods. Results are based on a threshold; significantly greater (e.g. 2X) absorbency compared to the negative control is considered positive. This code is based on, but not exclusive to, Lifecodes B-Screen assay.
Source: Regenstrief LOINC

Part Description

LP156721-5   HLA-DP+DQ+DR Ab.IgG
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.

Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens. Source: Regenstrief LOINC

Fully-Specified Name

Component
HLA-DP+DQ+DR Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IA

Additional Names

Short Name
HLA-DP+DQ+DR IgG Ser Ql IA
Display Name
HLA-DP+DQ+DR (class II) IgG IA Ql (S)
Consumer Name Alpha Get Info
HLA-DP+DQ+DR (class II) IgG antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
HLA
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
77639-3 HLA class I and II IgG panel - Serum or Plasma by Immunoassay

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) HLA-DP+DQ6DR IgG:PrThr:Punto temporal:Suero:Ord:IA
es-MX Spanish (Mexico) HLA-DP + DQ + DR Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
et-EE Estonian (Estonia) HLA-DP+DQ+DR antikehad.IgG:PrThr:Pt:S:Ord:IA
Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum
fr-CA French (Canada) HLA-DP+DQ+DR , IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FR French (France) HLA-DP+DQ+DR anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
fr-BE French (Belgium) HLA-DP+DQ+DR Anticorps. IgG:PrThr:Temps ponctuel:Sérum:Ordinal:IA
Synonyms: Anticorps
it-IT Italian (Italy) HLA-DP+DQ+DR Ab.IgG:PrThr:Pt:Siero:Ord:IA
Synonyms: anticorpi IgG anticorpo HLA tipizzazione tissutale antigeni-anticorpi Immunoassay Presenza o Soglia Pressione differenziale Punto nel tempo (episodio) Siero
nl-NL Dutch (Netherlands) HLA-DP+DQ+DR As.IgG:aanwezigheid:moment:serum:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA
pt-BR Portuguese (Brazil) HLA-DP+DQ+DR Ac.IgG:Limiar:Pt:Soro:Ord:Imunoensaio
ru-RU Russian (Russian Federation) HLA-DP+DQ+DR Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:IA
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) HLA-DP+DQ+DR Ab.IgG:MevcEşik:Zmlı:Ser:Srl:İA
Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) HLA-DP+DQ+DR 抗体.IgG:存在情况或阈值:时间点:血清:序数型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 HLA II 类;II 类 HLA HLA 抗原;人类白细胞抗原;human leukocyte antigen HLA-DP+DQ+DR Ab 人白细胞抗原 人类白细胞抗原 人类白细胞抗原(Human Leukocyte Antigen,HLA) 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 白细胞抗原

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72321-3