Version 2.77

Term Description

This term is used to identify a leukemia causing chromosomal translocation resulting in a gene fusion between ETV6 (12p13) and MN1 (22q11) genes. The term was created for (but not limited to) DNA Technology's HemaVision HV01-28N kit, a qualitative in vitro diagnostic test for 28 leukemia causing chromosomal alterations including more than 80 breakpoints plus associated mRNA splice variants. Reverse transcription followed by multiplex nested polymerase chain reactions (RT-PCR) and agarose gel electrophoresis are used to identify gene fusions caused by chromosomal translocations, gene deletions or inversions. Testing information is useful for predicting development of the disease and selection of treatment.
Source: Regenstrief LOINC

Fully-Specified Name

Component
t(12;22)(p13;q12.1)(ETV6,MN1) fusion transcript
Property
Arb
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
t(12;22)(ETV6,MN1) Bld/T Ql
Display Name
t(12;22)(p13;q12.1)(ETV6,MN1) fusion transcript Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
t(12;22)(p13;q12.1)(ETV6,MN1) fusion transcript analysis, Blood or tissue specimen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.40
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
72103-5 Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(12;22)(p13;q12.1)(ETV6,MN1) Tránscritos de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX Spanish (Mexico) t (12; 22) (p13; q12.1) (ETV6, MN1) transcripción de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR French (France) t(12;22)(p13;q12.1)(ETV6,MN1) transcrit de fusion:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) t(12;22)(p13;q12.1)(ETV6,MN1) , trascritto di fusione:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(12;22)(p13;q12.1)(ETV6,MN1) fusietranscript:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(12;22)(p13;q12.1)(ETV6,MN1) transcrição de fusão::Pt:Sg/Tecido:Ord:Genética molecular
ru-RU Russian (Russian Federation) t(12;22)(p13;q12.1)(ETV6,MN1) слияния транскрипт:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(12;22)(p13;q12.1)(ETV6,MN1) füzyon transkript:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN Chinese (China) t(12;22)(p13;q12.1)(ETV6,MN1) 融合转录物:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: ETS 变体基因 6 ETS 差异基因 6 ETS 突变体基因 6 ETS 突变基因 6 ETS 突变基因 6(ets variant gene 6,ETV6) TEL TEL 癌基因 TEL 癌基因(Tel oncogene) TEL 致癌基因 TEL1 任意;任意的;人工型 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内,用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 时刻;随机;随意;瞬间 易位 ETS 白血病 易位 ETS 白血病(Translocation ets leukemia,TEL) 易位(12;22)(p13;q12.1)(ETV6,MN1) 未作说明的组织;组织;组织 & 涂片 融合转录物(转录本、转录产物、转录子、转录);融合基因转录本;融合转录 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=70286-0