Version 2.77

Status Information

Status
TRIAL

Term Description

Participants are asked to fast for at least 9 hours (generally overnight) prior to the Oral Glucose Tolerance test. Participants are asked a series of exclusionary questions and then have an initial blood draw to determine Fasting Plasma Glucose levels. Participants are next asked to drink a calibrated dose (generally 75 grams / 10 ounces) of a dextrose solution (e.g., Trutol®) and have a second venipuncture 2 hours (plus or minus 15 minutes) after the first venipuncture. The plasma is separated from the blood via centrifugation and glucose concentration is determined via the hexokinase method. The Oral Glucose Tolerance Test includes a Fasting Plasma Glucose assay as the first step. Therefore performing the Oral Glucose Tolerance Test and the Fasting Plasma Glucose Assay for Diabetes Screening together will result collecting in the Fasting Plasma Glucose Assay twice. The Diabetes Working Group notes that an alternative to the single two-hour post load value is to establish a catheter and obtain samples for Serum Glucose concentrations at 0, 30, 60, 90 and 120 minutes. There are also protocols for more rapid sampling of Serum Glucose concentrations. In addition, the Diabetes Working Group notes that there are also protocols to collect samples for Serum Insulin concentrations at 0, 30, 60, 90 and 120 minutes and that this could be done at the same time as the Oral Glucose Tolerance Test. Such protocols would give extra specificity and information but would increase the burden on both the participant and investigator.
Source: Regenstrief LOINC

Reference Information

Type Source Reference
Article Consensus measures for Phenotypes and Exposures American Diabetes Association. (2009). Diagnosis and classification of diabetes mellitus. Diabetes Care, 32(Supplement 1), S62 - S67.
Article Consensus measures for Phenotypes and Exposures American Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61.
Citation Consensus measures for Phenotypes and Exposures Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Oral Glucose Tolerance Test (OGTT) Procedures Manual. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2005-2006
Citation Consensus measures for Phenotypes and Exposures Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Laboratory Procedures Manual. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2007-2008
Citation Consensus measures for Phenotypes and Exposures Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Shared Exclusion Questions for the MEC Examination. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2002. (questions 6 and 7)
Citation Consensus measures for Phenotypes and Exposures American Diabetes Association. (2008). Standards of medical care in diabetes - 2008. Diabetes Care, 31(Supplement 1), S12 - S54

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
62856-0 PhenX - oral glucose tolerance test protocol 141001
Indent66164-5 Did you eat or drink anything other than plain water after 11:30 last night?
Indent66165-2 When did you last eat or drink anything other than plain water?
Indent66166-0 Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
Indent66167-8 If Yes, record date
Indent66168-6 Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
Indent66169-4 If Yes, record date
Indent66170-2 Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
Indent66171-0 If Yes, record date
Indent66172-8 Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
Indent66173-6 If Yes, record date
Indent66182-7 Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
Indent66183-5 If Yes, record date
Indent66174-4 Are you currently pregnant?
Indent66175-1 {Is SP/Are you} now taking insulin?
Indent66176-9 {Is SP/Are you} now taking diabetic pills to lower {his/her}/your} blood sugar?
Indent66177-7 Do you have hemophilia?
Indent66178-5 Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66504-2 Exclusion Criteria
Indent8251-1 Service comment
Indent8251-1 Service comment
Indent29463-7 Body weight O [lb_av];kg
Indent66203-1 Record the amount of dextrose solution administered mL
Indent66204-9 Record the amount of dextrose solution the participant drank
Indent66205-6 Record whether all of the solution was consumed in 10 minutes
Indent66206-4 Record the number of minutes elapsed between consuming dextrose solution and administering the second blood draw min
Indent66208-0 Make of the equipment used to perform...
Indent74719-6 Manufacturer of the equipment used
Indent66240-3 Blood draw [PhenX]

Fully-Specified Name

Component
PhenX - oral glucose tolerance test protocol 141001
Property
-
Time
Pt
System
^Patient
Scale
-
Method
PhenX

Additional Names

Short Name
Oral glucose tolerance test proto

Survey Question

Source
PX141001

Basic Attributes

Class
PANEL.PHENX
Type
Clinical
First Released
Version 2.36
Last Updated
Version 2.67
Change Reason
Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type
Panel

Member of these Panels

LOINC Long Common Name
62787-7 PhenX domain - Diabetes

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) PhenX - protocolo de prueba de tolerancia a la glucosa oral 141001:-:Punto temporal:^ Paciente:-:PhenX
it-IT Italian (Italy) PhenX - test di tolleranza al carico orale di glucosio, protocollo:-:Pt:^Paziente:-:PhenX
Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio) Tolleranza al glucosio
ru-RU Russian (Russian Federation) PhenX - оральный к глюкозе толерантности тест протокол:-:ТчкВрм:^Пациент:-:PhenX
Synonyms: Толерантность к глюкозе Точка во времени;Момент
zh-CN Chinese (China) PhenX - 口服葡萄糖耐量试验方案 141001:-:时间点:^患者:-:PhenX
Synonyms: Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Consensus measures for Phenotypes and eXposures;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Glu tol;GTT;糖耐量;葡萄糖耐受;葡萄糖耐受力;葡萄糖耐受能力 Glu;Gluc;右旋糖;葡糖 PhenX - 口服糖耐量试验方案 141001;Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.PhenX;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.PhenX;Consensus measures for Phenotypes and eXposures;PhenX;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标;PhenX 医嘱组 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62856-0
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/62856-0