Version 2.77

Part Description

LP28780-2   Islet cell 512
Islet cell antigen (ICA) 512 is a receptor-tyrosine phosphatase-like protein associated with the secretory granules of neuroendocrine cells. ICA-512 is also known as protein tyrosine phosphatase-IA2 (PTP-IA2) or tyrosine phosphatase (IA2). It is an autoantigen of type 1 diabetes. This is NOT the same as pancreatic islet cell. Studies on type-1 diabetic patient's relatives found that the development of one or more islet autoantibodies (including IA-2 antibody) was an early indicator of the relatives' progression to type-1 diabetes. Autoantibody profiles identifying patients destined to develop type-1 diabetes are usually detectable before age three. One study found that for relatives seropositive for IA-2 antibody, the likelihood of developing type-1 diabetes mellitus within five-years was 65.3%. Some type-1 diabetic patients are originally diagnosed as having type-2 diabetes due to symptom onset in adulthood, societal obesity, and initial insulin-independence. Detection of one or more islet auto-antibodies (including IA-2) may be used to distinguish these patients with "latent autoimmune diabetes" from type-2 diabetics. Source: Regenstrief Institute

Fully-Specified Name

Component
Islet cell 512 Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
Islet Cell512 Ab Ser IA-aCnc
Display Name
Islet cell 512 Ab IA Qn (S)
Consumer Name Alpha Get Info
Islet cell 512 antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
3926

Member of these Groups Get Info

LOINC Group Group Name
LG12513-4 Islet cell 512 Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Inselzellantigen 512 Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay
es-ES Spanish (Spain) Célula de los islotes 512 Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Celda de islotes 512 Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
fr-CA French (Canada) ICA 512 d'îlots de Langerhans , Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR French (France) Cellules îlots 512 anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE French (Belgium) ICA 512 d'îlots de Langerhans Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
Synonyms: Anticorps
it-IT Italian (Italy) Isola 512 cellula Ab:ACnc:Pt:Siero:Qn:IA
Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) islet antigeen-2 As:eenheid/volume:moment:serum:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA IA-2
pl-PL Polish (Poland) Komórki wyspowe 512 Ab:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna
Synonyms: Antygen 512 komórek wyspowych
pt-BR Portuguese (Brazil) Ilhotas células 512 Ac:#N/A:Pt:Soro:Qn:Imunoensaio
Synonyms: ICA; ICA512; Islet Cell512; IA-2; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Островковая клетка 512 Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Adacık hücresi 512 Ab:SçKons:Zmlı:Ser:Kant:İA
Synonyms: Ak İmmünölçüm, immünoassay
uk-UA Ukrainian (Ukraine) Острівцева клітина 512 Антитіла:Довільна Концентрація:МоментЧасу:Сироватка:Кількісно:Імуноаналіз
Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Arbitrary concentration; Autoantibodies; Autoantibody; EIA; ELFA; ELISA; Endocrine; Endocrinology; Enzyme immunoassay; IA2; IA-2; IA2-ab; IAA; ICA; ICA512; ICA-512; Islet Cell512; MEIA; Point in time; protein tyrosine phosphatase-like protein IA2; PtP-IA2; QNT; Quan; Quant; Quantitative; Random; Serology; Serum; SR; SUDS; Tyrosine phosphatase
zh-CN Chinese (China) 岛细胞 512 抗体:任意型浓度:时间点:血清:定量型:免疫测定法
Synonyms: Ab;自身抗体 IA-2;ICA;ICA512;小岛细胞 512;小岛细胞 512（Islet cell 512）;岛细胞 512（Islet cell 512）;这里的岛细胞（ Islet Cell）并不等同于胰岛细胞（ Pancreatic Islet Cell） ICA ICA512 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 小岛细胞 512 Ab 小岛细胞 512 抗体 岛细胞 512 Ab 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=56718-0