Version 2.77

Part Description

LP36432-0   Hepatitis B virus YMDD mutation
In hepatitis B, lamivudine resistance was first described in the YMDD locus of the HBV reverse transcriptase gene. The HBV reverse transcriptase gene is 344 amino acids long and occupies codons 349 to 692 on the viral genome. The most commonly encountered resistance mutations are M204V/I/S. The change in amino acid sequence from YMDD to YIDD results in a 3.2 fold reduction in the error rate of the reverse transcriptase, which correlates with a significant growth disadvantage of the virus. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Hepatitis B virus YMDD mutation
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
HBV YMDD Mut SerPl Ql NAA+probe
Display Name
HBV YMDD NAA+probe Ql
Consumer Name Alpha Get Info
Hepatitis B virus (HBV) YMDD, Blood

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
10644

Member of these Groups Get Info

LOINC Group Group Name
LG32752-4 Hepatitis B virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-B-Virus YMDD-Mutation:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Gen GDAP1:PrThr:Punto temporal:Suero o Plasma:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Virus de la hepatitis B YMDD:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Mutants YMDD du virus de l'hépatite B:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Hépatite B virus mutation YMDD:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:PCR amplification de cible
fr-BE French (Belgium) Mutants YMDD du virus de l'hépatite B:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:Sonde avec amplification de la cible
Synonyms: HBV
it-IT Italian (Italy) Epatite B virus, mutazione YMDD:PrThr:Pt:Siero/Plasma:Ord:Sonda.amp.tar
Synonyms: HBV Mutazione YMDD del virus dell''epatite B Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) Hepatitis B-virus YMDD mutatie:aanwezigheid:moment:serum of plasma:ordinaal:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Hepatite B vírus YMDD mutação:Ident:Pt:Sor/Plas:Nom:Sonda com limite de detecção da amplificação de alvo
Synonyms: ; HBV YMDD Mut; HepB; Hep B; Identity or presence; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Nominal; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Mutations; Hepatit; Hepatis; Microbiology
ru-RU Russian (Russian Federation) Гепатит B вирус YMDD мутация:PrThr:ТчкВрм:Сыв/Плаз:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Плазма Порядковый Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatit B virüsü YMDD mutasyonu:MevcEşik:Zmlı:Ser/Plaz:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 乙型肝炎病毒 YMDD 突变:存在情况或阈值:时间点:血清/血浆:序数型:探针法.基因扩增.靶向
Synonyms: B 型 HBV YMDD Mut;HBV YMDD 突变;Hep B YMDD 突变;乙肝病毒 YMDD 突变;肝炎病毒 B 型 YMDD 突变 HBV;Hep B;乙型肝炎;乙肝;乙肝病毒;肝炎病毒 B 型 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 扩增型 扩增性 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 经过扩增的 肝 脱氧核糖核酸探针 血清或血浆

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43279-9