Version 2.77

Part Descriptions

LP36049-2   HLA-B*57:01
Part of HLA-B57 allele family that is associated with Abacavir hypersensitivity reaction (AHSR) Source: Regenstrief Institute

LP36049-2   HLA-B*57:01
The human leukocyte antigen B (HLA-B) plays an important role in how the immune system recognizes and responds to pathogens. HLA-B belongs to a class of molecules that are found on the surface of most cells. These molecules are responsible for presenting peptides to immune cells. Peptides derived from normal human proteins are recognized as such, whereas foreign peptides derived from pathogens trigger an immune response. The antiretroviral medication abacavir specifically interacts with HLA-B*57:01 and alters the repertoire of self-peptides that are presented to T lymphocytes, which activates an immune reaction known as a hypersensitivity reaction. PMID: 24561393 See https://www.pharmgkb.org/gene/PA35056 for more information and dosing guidelines for drugs impacted by HLA-B genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium

Fully-Specified Name

Component
HLA-B*57:01
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method

Additional Names

Short Name
HLA-B*57:01 Spec Ql
Display Name
HLA-B*57:01 Ql (Specimen)
Consumer Name Alpha Get Info
HLA-B*57:01, Specimen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
HLA
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.73
Change Reason
Changed answer list from "Normative" to "Example" to fit the current LOINC model.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
7272

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) HLA-B*57:01:PrThr:Punto temporal:XXX:Ord:
es-MX Spanish (Mexico) HLA-B * 57:1:Presencia o umbral:Punto temporal:XXX:Ordinal
et-EE Estonian (Estonia) HLA-B5701:PrThr:Pt:XXX:Ord:
Synonyms: Järgarvuline Juhuslik Täpsustamata materjal
fr-CA French (Canada) HLA-B*57:01:Présence-Seuil:Temps ponctuel:XXX:Ordinal:
fr-FR French (France) HLA-B*57:01:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:
fr-BE French (Belgium) HLA-B5701:PrThr:Temps ponctuel:XXX:Ordinal:
it-IT Italian (Italy) HLA-B*57:01:PrThr:Pt:XXX:Ord:
Synonyms: HLA tipizzazione tissutale antigeni-anticorpi Presenza o Soglia Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 사람 조직적합 복합체 유도 항원-B5701:임의농도:검사시점:XXX:순위척도:
nl-NL Dutch (Netherlands) HLA-B*5701:aanwezigheid:moment:XXX:ordinaal:
pt-BR Portuguese (Brazil) HLA-B5701:ACnc:Pt:XXX:Ord:
Synonyms: HLA-B57; Human Leukocyte Antigen; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; HLA ANTIGEN
ru-RU Russian (Russian Federation) HLA-B*5701:PrThr:ТчкВрм:XXX:Пор:
Synonyms: Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) HLA-B*5701:MevcEşik:Zmlı:XXX:Srl:
Synonyms: Mevcut
zh-CN Chinese (China) HLA-B*57:01:存在情况或阈值:时间点:XXX:序数型:
Synonyms: B 型 HLA 抗原;人类白细胞抗原;human leukocyte antigen HLA-B5701;HLA-B57;与阿巴卡韦超敏反应（ Abacavir hypersensitivity reaction，AHSR）相关联的 HLA-B57 等位基因家族的组成部分 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 人白细胞抗原 人类白细胞抗原 人类白细胞抗原（Human Leukocyte Antigen，HLA） 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 白细胞抗原

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=42358-2