39320-7
Abnormal Prion Protein [Presence] in Tissue by Immunoblot
Active
Part Description
LP35078-2 Prion protein.abnormal
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of progressive conditions (encephalopathies) that affect the brain and nervous system of many animals, including humans. According to the most widespread hypothesis they are transmitted by abnormal prions, though some other data suggest an involvement of a Spiroplasma infection. Mental and physical abilities deteriorate and a myriad of tiny holes appear in the cortex causing it to appear like a sponge (hence spongiform) when brain tissue obtained at autopsy is examined under a microscope. The disorders cause impairment of brain function, including memory changes, personality changes and problems with movement that worsen over time. Most TSEs are sporadic and occur in animals. Prion diseases of animals in include classical bovine spongiform encephalopathy (BSE) (C-type), atypical (H or L-type) BSE, Scrapie, atypical scrapie, Nor98, and chronic wasting disease (CWE). H-type and L-type BSE were named based on abnormal prion bands migrating to a higher (H) or lower (L) position on western blot analysis compared to the classical BSE (C-type) prion protein. Prion diseases of humans include classic Creutzfeldt-Jakob disease, new variant Creutzfeldt-Jakob disease (nvCJD, a human disorder related to Bovine spongiform encephalopathy), Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia and kuru. These conditions form a spectrum of diseases with overlapping signs and symptoms.
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Source: Wikipedia, Transmissible spongiform encephalopathy
Fully-Specified Name
- Component
- Prion protein.abnormal
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- IB
Additional Names
- Short Name
- Abn Prion Prot Tiss Ql IB
- Display Name
- Abnormal Prion Protein IB Ql (Tiss)
- Consumer Name Alpha Get Info
- Abnormal prion protein, Tissue
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.65
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Prionenprotein.abnorm: |
| es-ES | Spanish (Spain) | Proteína priónica anormal: |
| es-MX | Spanish (Mexico) | Proteína priónica anormal: |
| fr-CA | French (Canada) | Protéines prion.anormales: |
| fr-FR | French (France) | Protéine prion anormale: |
| fr-BE | French (Belgium) | Protéines prion.anormales: |
| it-IT | Italian (Italy) | Proteina prionica.anormale: Synonyms: Immunoblot (IB) Microbiologia Presenza o Soglia Proteina Prionica Anormale Punto nel tempo (episodio) Tessuto & |
| ko-KR | Korean (Korea, Republic Of) | 프리온 단백.이상: |
| nl-NL | Dutch (Netherlands) | prioneiwit.abnormaal: Synonyms: IB |
| pt-BR | Portuguese (Brazil) | Proteína prion.anormal: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Прионный протеин.аномальный: Synonyms: Белок Иммуноблот (ИБ) Порядковый Прионный белок.аномальный Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | Prion protein.anormal: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 朊病毒蛋白.异常: Synonyms: BSE; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=39320-7
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright