Version 2.77

Part Description

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Fully-Specified Name

Component
Valproate.free/Valproate.total
Property
MFr
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Valproate Free MFr SerPl
Display Name
Valproate Free/Total valproate [Mass fraction]
Consumer Name Alpha Get Info
Free valproate/Valproate.total, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.07
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
5529

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) valproato.libre/valproato.total:fracción de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Valproico libre/Valproato total:Fracción de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Valproato.libre/Valproato.total:Fracción de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Valproaat.vaba/valproaat.üld:MFr:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Valproate.libre/Valproate.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Valproate libre/valproate total:Fraction massique:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Valproate.libre/Valproate.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Valproato.libero/Valproato.totale:MFr:Pt:Siero/Plasma:Qn:
Synonyms: Frazione di massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Valproato Libero
ko-KR Korean (Korea, Republic Of) 유리벨프로에이트/총벨프로에이트:질량분획:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) valproaat.vrije/valproaat.totaal:massafractie:moment:serum of plasma:kwantitatief:
Synonyms: valproinezuur; 2-propylpentaanzuur
pt-BR Portuguese (Brazil) Valproato.livre/Valproato.total:MFr:Pt:Sor/Plas:Qn:
Synonyms: Valproic acid; Depakene; Mass fraction; Percent; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; Tot; Totl; FR; Non-protein bound; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Вальпроат.свободный/Вальпроат.общий:МассДол:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая доля Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Valproat.serb/Valproat.total:KütlFr:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 2-丙基戊酸.游离型/2-丙基戊酸.总计:质量分数:时间点:血清/血浆:定量型:
Synonyms: 2-丙基戊酸.游离;游离 2-丙基戊酸;游离型 2-丙基戊酸 2-丙基戊酸总计 2-丙基戊酸钠;C8H15NaO2;丙基戊酸;丙戊酸;VPA;Valproate;Valproic Acid MFr 全体数量 全部 共计 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 毒品 毒品类 汇总 游离 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

Example Units

Unit Source
% Example UCUM Units
% REGENSTRIEF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=32283-4