Version 2.77

Part Descriptions

LP18172-4   Interferon.beta
Beta interferon is a recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b. Source: National Cancer Institute, Beta interferon

LP38708-1   Interferon.beta Ab
Highly elevated levels of neutralizing antibodies (NAbs >1:100) to interferon-beta used as therapy in patients with Multiple Sclerosis have been reported to correlate with predictable loss of interferon-beta bioactivity. In patients with elevated NAb levels from >1:20 to <1:100, interferon-beta bioactivity may still be present, but does not necessarily correlate to the exact NAb titer, and continued patient monitoring may be warranted. There is no apparent loss of interferon-beta bioactivity in patients who test positive in the binding antibody assay, but
negative for NAbs; however, continued patient monitoring may also be warranted in this instance as well. Source: Quest Diagnostics Inc., Interferon-beta 1a (IFNB-1a) Antibody

Fully-Specified Name

Component
Interferon.beta Ab
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method

Additional Names

Short Name
IFN-B Ab SerPl Ql
Display Name
Interferon beta Ab Ql
Consumer Name Alpha Get Info
Interferon beta antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.03
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
12753

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Interferon.beta Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:
es-AR Spanish (Argentina) anticuerpo contra interferón.beta 1:concentración arbitraria:punto en el tiempo:suero/plasma:ordinal:
es-ES Spanish (Spain) Interferon beta Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:
es-MX Spanish (Mexico) Interferon.beta Ab:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:
et-EE Estonian (Estonia) Beetainterferoon antikehad:PrThr:Pt:S/P:Ord:
Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA French (Canada) Interféron.bêta , Ac:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-FR French (France) Interféron bêta anticorps:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:
fr-BE French (Belgium) Interféron.béta Ac:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:
Synonyms: Anticorps IF If.béta
it-IT Italian (Italy) Interferone.beta Ab:PrThr:Pt:Siero/Plasma:Ord:
Synonyms: anticorpo Interferone beta Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) 인터페론.베타 항체:임의농도:검사시점:혈청/혈장:순위척도:
nl-NL Dutch (Netherlands) interferon.bèta As:aanwezigheid:moment:serum of plasma:ordinaal:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Interferon.beta Ac:ACnc:Pt:Sor/Plas:Ord:
Synonyms: ; B-IFN; Betaferon; B-IFN 1A+1B; INF-B; IFN; Arbitrary concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; B; Serology
ru-RU Russian (Russian Federation) Интерферон.бета Ат:PrThr:ТчкВрм:Сыв/Плаз:Пор:
Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) İnterferon.beta Ab:MevcEşik:Zmlı:Ser/Plaz:Srl:
Synonyms: Ak Mevcut
zh-CN Chinese (China) 干扰素.beta 抗体:存在情况或阈值:时间点:血清/血浆:序数型:
Synonyms: Ab;自身抗体 B beta 干扰素 Ab beta 干扰素;B-IFN;B-IFN 1A+1B;INF-B;β干扰素;干扰素 beta;干扰素.β;干扰素β beta 干扰素抗体 B-IFN Ab B-IFN 抗体 IFN INF-B Ab INF-B 抗体 β β干扰素 Ab β干扰素抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 干扰素 beta Ab 干扰素 beta 抗体 干扰素.beta Ab 干扰素.β Ab 干扰素.β抗体 干扰素β Ab 干扰素β抗体 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆 贝塔

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29647-5