Version 2.77

Part Description

LP21418-6   Carboxyhemoglobin
Carboxyhemoglobin, a complex of hemoglobin and carbon monoxide, is a marker of exposure to inhaled carbon monoxide (CO). CO gas is produced from almost any fire as the result of incomplete combustion to CO2, and the normal individual will have about 1 or 2 % of their hemoglobin in the form of carboxyhemoglobin, and up to 5% depending on environmental circumstances. Smokers can have levels as high as 10% or even higher. Poisoning with CO generally results from improperly vented furnaces, automobile exhaust, and fires, with carboxyhemoglobin:hemoglobin ratios of 10-30% found in symptomatic individuals and 30-90% in fatalities. With a 230 fold greater affinity, inhaled CO avidly replaces oxygen at its hemoglobin binding site. In addition, replacing even one of the 4 sites of the hemoglobin tetramer with CO prevents dissociation of the remaining 3 oxygen moieties to tissue (known as left shift of O2 dissociation curve). As a result, hemoglobin remains red and skin color is rosy despite physiologic anoxia. Although measuring carboxyhemoglobin can confirm carbon monoxide poisoning, the level does not always correlate with the clinical picture; carbon monoxide poisoning involves other mechanisms as well, including binding to myoglobin, cytochrome oxidase, and direct effects on the central nervous system. Source: Regenstrief LOINC

Fully-Specified Name

Component
Carboxyhemoglobin/Hemoglobin.total
Property
MFr
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Short Name
COHgb MFr Bld
Display Name
Carboxyhemoglobin (Bld) [Mass fraction]
Consumer Name Alpha Get Info
Carboxyhemoglobin/Total Hgb, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
663

Member of these Panels

LOINC Long Common Name
24343-6 Gas and Carbon monoxide panel - Blood
62611-9 PhenX domain - Respiratory

Member of these Groups Get Info

LOINC Group Group Name
LG6297-8 Carboxyhemoglobin/Hemoglobin.total|MFr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: CO-Hämoglobin
de-DE German (Germany) Carboxyhämoglobin/Hämoglobin.gesamt:Massenfraktion:Zeitpunkt:Blut:Quantitativ:
Synonyms: COHb; CO-Hemoglobin
es-AR Spanish (Argentina) carboxihemoglobina/hemoglobina.total:fracción de masa:punto en el tiempo:sangre:cuantitativo:
es-MX Spanish (Mexico) Carboxihemoglobina / Hemoglobina total:Fracción de masa:Punto temporal:Sangre:Cuantitativo:
es-ES Spanish (Spain) Carboxihemoglobina/Hemoglobina.total:Fracción de masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Karboksühemoglobiin/hemoglobiin.üld:MFr:Pt:B:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA French (Canada) Carboxyhémoglobine/Hémoglobine.totale:Fraction de masse:Temps ponctuel:Sang:Quantitatif:
fr-BE French (Belgium) Carboxyhémoglobine/Hémoglobine.totale:Fraction de masse:Temps ponctuel:Sang:Quantitatif:
Synonyms: Hb Hb.totale HbCO
fr-FR French (France) Carboxyhémoglobine/hémoglobine totale:Fraction massique:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Carbossiemoglobina/Emoglobina.totale:MFr:Pt:Sangue:Qn:
Synonyms: Chimica Frazione di massa Punto nel tempo (episodio) Sangue
ko-KR Korean (Korea, Republic Of) 일산화탄소 혈색소/총혈색소:질량분획:검사시점:전혈:정량:
nl-NL Dutch (Netherlands) carboxyhemoglobine/hemoglobine.totaal:massafractie:moment:bloed:kwantitatief:
pl-PL Polish (Poland) Karboksyhemoglobina/hemoglobina całkowita:frakcja masowa:punkt w czasie:krew:ilościowy:
Synonyms: Karboksyhemoglobina Karboksyhemoglobina/Hemoglobina całkowita
pt-BR Portuguese (Brazil) Carboxihemoglobina/Hemoglobina.total:MFr:Pt:SgTotal:Qn:
Synonyms: ; COHgb; Carboxyhemoglob; Carbon monoxide.hemoglobin; COHb; HbCO; Carbonyl hemoglobin; Carbonmonoxyhemoglobin; CO haemoglobin; CO hemoglobin; Carboxyhaemoglobin; Hemoglobin bound with carbon dioxide; Carbonyl Hgb; Carbonyl haemoglobin; Hb; Haemoglobin; Mass fraction; Percent; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Tot; Totl; Chemistry
ru-RU Russian (Russian Federation) Карбоксигемоглобин/Гемоглобин.общий:МассДол:ТчкВрм:Кр:Колич:
Synonyms: Количественный Кровь Массовая доля Точка во времени;Момент
tr-TR Turkish (Turkey) Karboksihemoglobin/Hemoglobin.total:KütlFr:Zmlı:Kan:Kant:
uk-UA Ukrainian (Ukraine) Карбоксигемоглобін/Гемоглобін.загальний:Масова Фракція:МоментЧасу:Кров:Кількісно:
Synonyms: Blood; Carbon monoxide.hemoglobin; Carbonmonoxyhemoglobin; Carbonyl haemoglobin; Carbonyl hemoglobin; Carbonyl Hgb; Carboxyhaemoglobin; Carboxyhemoglob; Chemistry; CO haemoglobin; CO hemoglobin; COHb; COHgb; Haemoglobin; Hb; HbCO; Hemoglobin bound with carbon dioxide; Hgb; Lung; Mass Fraction; Percent; Point in time; Pulmonary; Pulmonology; QNT; Quan; Quant; Quantitative; Random; Respiratory; Tot; Totl; UniversalLabOrders; WB; Whole blood
zh-CN Chinese (China) 碳氧血红蛋白/血红蛋白.总计:质量分数:时间点:全血:定量型:
Synonyms: CO 血红蛋白;CO.血红蛋白;COHb;COHgb;一氧化碳.血红蛋白;羧络血红朊;羧络血红蛋白;羧血蛋白;羰络血红朊 MFr 全体数量 全部 共计 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 总 总和 总数 总血红蛋白 总量 总额 时刻;随机;随意;瞬间 氧血红蛋白;血红朊;血红素;血色素 汇总 血;血液

Example Units

Unit Source
% Example UCUM Units
% REGENSTRIEF
% eCHN
% SAT REGENSTRIEF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=20563-3